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Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest

by Storm, Christian , Lange, Theis , Undén, Johan , Brunetti, Iole , Wise, Matt P , Morgan, Matt P.G , Ullén, Susann , Düring, Joachim , Jakobsen, Janus C , McGuigan, Peter , Vignon, Philippe , Lilja, Gisela , Nordberg, Per , Annborn, Martin , Hovdenes, Jan , Bělohlávek, Jan , Cassina, Tiziano , Dankiewicz, Josef , Pelosi, Paolo , Christensen, Steffen , Callaway, Clifton , Oddo, Mauro , Haenggi, Matthias , Lundin, Andreas , Faessler, Edith , Jaubert, Paul , Thomas, Matthew , Awad, Akil , Grejs, Anders M , Abed-Maillard, Samia , Friberg, Hans , Schrag, Claudia , Maggiorini, Marco , Navarra, Leanlove , Karamasis, Grigoris V , Cronberg, Tobias , Joannidis, Michael , Nichol, Alistair D , Young, Paul J , Chew, Michelle S , Keeble, Thomas R , Borgquist, Ola , Rylander, Christian , Schmidbauer, Simon , Langeland, Halvor , Cole, Jade M , Levin, Helena , Eastwood, Glenn M , Saxena, Manoj , Leithner, Christoph , Bewley, Jeremy , Nielsen, Niklas , Smid, Ondrej , Bjørkholt Olsen, Roy , Kirkegaard, Hans , Solar, Miroslav , Sweet, Katie , Otáhal, Michal , Cariou, Alain , Levis, Anja , Hollenberg, Jacob , Wendel Garcia, Pedro D , Erlinge, David , Taccone, Fabio S

in Adverse events / Ambulance services / american-heart-association / Anestesi och intensivvård / Anesthesiology and Intensive Care / Arrhythmia / Body temperature / Cardiac arrest / Cardiology and Cardiovascular Disease / cardiopulmonary-resuscitation / Clinical Medicine / Coma / COVID-19 / european resuscitation council / Fever / General & Internal Medicine / Generalized linear models / guidelines / Heart / Heart attacks / Hemodynamics / Hospitals / Hypothermia / Intervention / Kardiologi och kardiovaskulära sjukdomar / Klinisk medicin / Medical and Health Sciences / Medical prognosis / Medicin och hälsovetenskap / Patients / Quality of life / Questionnaires / Sepsis / Statistical analysis / targeted temperature management

2021

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2021

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2021

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Journal Article

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest

Storm, Christian,

Lange, Theis,

Undén, Johan,

Brunetti, Iole,

Wise, Matt P,

Morgan, Matt P.G,

Ullén, Susann,

Düring, Joachim,

Jakobsen, Janus C,

McGuigan, Peter,

Vignon, Philippe,

Lilja, Gisela,

Nordberg, Per,

Annborn, Martin,

Hovdenes, Jan,

Bělohlávek, Jan,

Cassina, Tiziano,

Dankiewicz, Josef,

Pelosi, Paolo,

Christensen, Steffen,

Callaway, Clifton,

Oddo, Mauro,

Haenggi, Matthias,

Lundin, Andreas,

Faessler, Edith,

Jaubert, Paul,

Thomas, Matthew,

Awad, Akil,

Grejs, Anders M,

Abed-Maillard, Samia,

Friberg, Hans,

Schrag, Claudia,

Maggiorini, Marco,

Navarra, Leanlove,

Karamasis, Grigoris V,

Cronberg, Tobias,

Joannidis, Michael,

Nichol, Alistair D,

Young, Paul J,

Chew, Michelle S,

Keeble, Thomas R,

Borgquist, Ola,

Rylander, Christian,

Schmidbauer, Simon,

Langeland, Halvor,

Cole, Jade M,

Levin, Helena,

Eastwood, Glenn M,

Saxena, Manoj,

Leithner, Christoph,

Bewley, Jeremy,

Nielsen, Niklas,

Smid, Ondrej,

Bjørkholt Olsen, Roy,

Kirkegaard, Hans,

Solar, Miroslav,

Sweet, Katie,

Otáhal, Michal,

Cariou, Alain,

Levis, Anja,

Hollenberg, Jacob,

Wendel Garcia, Pedro D,

Erlinge, David,

Taccone, Fabio S

2021

Overview

This trial randomly assigned patients with coma after out-of-hospital cardiac arrest to undergo targeted hypothermia at 33°C or normothermia with treatment of fever. At 6 months, there were no significant between-group differences regarding death or functional outcomes.

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Publisher

Massachusetts Medical Society

Subject

Adverse events

/ Ambulance services

/ american-heart-association

/ Anestesi och intensivvård

/ Anesthesiology and Intensive Care

/ Arrhythmia

/ Body temperature