Journal Article

Incidence of near-death experiences in patients surviving a prolonged critical illness and their long-term impact: a prospective observational study

Cassol, Héléna, Massart, Quentin, Martial, Charlotte, Laureys, Steven, Gosseries, Olivia, Misset, Benoit, Dams, Laurence, Choquer, Laila, Dardenne, Nadia, Rousseau, Anne-Françoise

2023

Overview

Background So far, the few prospective studies on near-death experience (NDE) were carried out only in intensive care unit (ICU) patients with homogeneous aetiologies, such as cardiac arrest or trauma survivors. The aims of this 1-year prospective and monocentric study were to investigate the incidence of NDE in ICU survivors (all aetiologies) as well as factors that may affect its frequency, and to assess quality of life up to 1 year after enrolment. Methods We enrolled adults with a prolonged ICU stay (> 7 days). During the first 7 days after discharge, all eligible patients were assessed in a face-to-face interview for NDE using the Greyson NDE scale, dissociative experiences using the Dissociative Experience Scale, and spirituality beliefs using the WHOQOL-SRPB. Medical parameters were prospectively collected. At 1-year after inclusion, patients were contacted by phone to measure quality of life using the EuroQol five-dimensional questionnaire. Results Out of the 126 included patients, 19 patients (15%) reported having experienced a NDE as identified by the Greyson NDE scale (i.e. cut-off score ≥ 7/32). In univariate analyses, mechanical ventilation, sedation, analgesia, reason for admission, primary organ dysfunction, dissociative and spiritual propensities were associated with the emergence of NDE. In multivariate logistic regression analysis, only the dissociative and spiritual propensity strongly predicted the emergence of NDE. One year later (n = 61), the NDE was not significantly associated with quality of life. Conclusions The recall of NDE is not so rare in the ICU. In our cohort, cognitive and spiritual factors outweighed medical parameters as predictors of the emergence of NDE. Trial registration This trial was registered in Clinicaltrials.gov in February 2020 ( NCT04279171 ).

• Publisher: BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
• Subject: Adult / Body temperature / Brief Report / Catastrophic illness / Clinical outcomes / Complications and side effects / Critical care / Critical Care Medicine / Critical Illness - epidemiology / Death / Delirium / Dissociation / Emergency Medicine / Health aspects / Health psychology / Human health sciences / Humans / Incidence / Intensive / Intensive care / Medicine / Medicine & Public Health / Memory / Near death experiences / Near-death experience / Neurologie / Neurology / Observational studies / Patient outcomes / Patients / Physiology / Post traumatic stress disorder / Prospective Studies / Prospective study / Quality of Life / Questionnaires / Sciences de la santé humaine / Statistics