Asset Details
Do you wish to reserve the book?
Determinants of genetic diversity
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Determinants of genetic diversity
Do you wish to request the book?
Determinants of genetic diversity
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Determinants of genetic diversity
2016
Overview
Key Points
Lewontin's paradox — the much larger variation in species abundance than in genetic diversity — is closer to being explained.
The reproductive strategy of species has an impact on genome-wide diversity, providing a connection between population dynamic processes and the long-term effective population size (
N
e
).
Selection at linked sites also affects genome-wide diversity, but not to an extent that it is sufficient alone to explain Lewontin's paradox.
Selection and demography, among other factors, contribute to variation in
N
e
within genomes and leads to variation in diversity in different genomic regions of the same species.
The degree of genetic diversity differs greatly among species and across genomic loci within genomes. The wide ranges in genetic diversity have important implications, including for evolution, conservation and management of wild and domesticated species. In this Review, the authors discuss how genome-scale sequencing strategies are providing insight into the varied determinants of genetic variation both among species and across genomic regions.
Genetic polymorphism varies among species and within genomes, and has important implications for the evolution and conservation of species. The determinants of this variation have been poorly understood, but population genomic data from a wide range of organisms now make it possible to delineate the underlying evolutionary processes, notably how variation in the effective population size (
N
e
) governs genetic diversity. Comparative population genomics is on its way to providing a solution to 'Lewontin's paradox' — the discrepancy between the many orders of magnitude of variation in population size and the much narrower distribution of diversity levels. It seems that linked selection plays an important part both in the overall genetic diversity of a species and in the variation in diversity within the genome. Genetic diversity also seems to be predictable from the life history of a species.
Publisher
Nature Publishing Group UK,Nature Publishing Group
