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Platelet-to-lymphocyte ratio and C-reactive protein as markers for colorectal polyp histological type
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Platelet-to-lymphocyte ratio and C-reactive protein as markers for colorectal polyp histological type
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Journal Article
Platelet-to-lymphocyte ratio and C-reactive protein as markers for colorectal polyp histological type
2021
Overview
Background
The platelet-to-lymphocyte ratio (PLR) and C-reactive protein (CRP) level are markers that have been reported to predict the histological type of various tumors, and here, we evaluated their utility in predicting colorectal polyp histological types.
Methods
We retrospectively reviewed 172 patients with colorectal polyps who underwent endoscopic polypectomy. The associations between histological type and clinicopathologic parameters were assessed by multivariate analysis.
Results
The optimal PLR and CRP cut-off values were 113.32 and 0.39, respectively. The PLR (
P
= 0.002) and CRP (
P
= 0.009) values were associated with the histological type according to the univariate analysis, whereas low PLR (
P
≤ 0.001) and CRP (
P
= 0.017) values were independent risk factors in the multivariate analysis together with maximum tumor diameter (
P
≤ 0.001) and tumor number (
P
= 0.0014).
Conclusions
Preoperative PLR and CRP are correlated with the colorectal polyp histological type.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Aged
/ Biomedical and Life Sciences
/ C-Reactive Protein - analysis
/ Colorectal Neoplasms - blood
/ Colorectal Neoplasms - diagnosis
/ Colorectal Neoplasms - pathology
/ Colorectal Neoplasms - surgery
/ Female
/ Health Promotion and Disease Prevention
/ Humans
/ Intestinal Mucosa - pathology
/ Male
/ Medical and radiation oncology
/ Oncology
/ Platelet-to-lymphocyte ratio (PLR)
/ Polyps
/ Proteins
/ Rectus Abdominis - pathology
/ Tumors
