Journal Article

Sclerosing mesenteritis and mesenteric panniculitis – clinical experience and radiological features

Sjöberg, Klas, Nyberg, Lisa, Björk, Jan, Ekberg, Olle, Vigren, Lina, Björkdahl, Peter

2017

Overview

Background Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term for idiopathic inflammatory conditions in the mesentery. Mesenteric panniculitis (MP) is a radiological finding and its relation to clinical SM is not fully understood. The aims of this study were to determine whether any correlation could be found between the radiological findings and the clinical disease course. Methods Patients observed due to idiopathic inflammation of the mesentery were identified. If SM could be verified histologically or MP radiologically, the patients were included in this descriptive retro perspective study. Results Typical radiological changes were observed in 27 patients. A majority (23/27) of these patients had mild to moderate symptoms. This group with typical radiology was labelled MP. Four patients were included due to histologically verified disease but had uncharacteristic radiology involving multiple compartments of the abdomen. All four had marked systemic inflammation, fever and fluctuating radiologic findings. Three had severe disease with multiple hospitalisations and complications but responded promptly to corticosteroids. This group was denoted SM. Conclusions We have identified two subgroups of patients; firstly, MP with stable and characteristic radiologic changes and secondly SM with atypical radiology and a more aggressive clinical course. We propose that the term SM should be reserved for this latter condition.

• Publisher: BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
• Subject: Adult / Aged / Care and treatment / Clinical classification / Clinical Medicine / Corticosteroids / Diagnosis / Diagnosis, Differential / Disease Progression / Female / Fever / Gastroenterology / Hepatology / Histology / Histopathology / Humans / Inflammation / Internal Medicine / Intestinal disorders / Kirurgi / Klinisk medicin / Lymphatic system / Male / Medical and Health Sciences / Medical records / Medicin och hälsovetenskap / Medicine / Medicine & Public Health / Mesenteric panniculitis / Mesenteritis / Mesentery / Middle Aged / NMR / Nuclear magnetic resonance / Panniculitis / Panniculitis - classification / Panniculitis - diagnostic imaging / Panniculitis, Peritoneal - classification / Panniculitis, Peritoneal - diagnostic imaging / Patients / Prospective Studies / Radiography - methods / Radiological classification / Radiology / Registries / Research Article / Retractile mesenteritis / Retrospective Studies / Risk factors / Studies / Surgery / Sweden / Terminology as Topic