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Strengthening ethics review of the development of artificial intelligence (AI) systems in health research: a guide for research ethics committees in Uganda
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Strengthening ethics review of the development of artificial intelligence (AI) systems in health research: a guide for research ethics committees in Uganda
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Journal Article
Strengthening ethics review of the development of artificial intelligence (AI) systems in health research: a guide for research ethics committees in Uganda
2025
Overview
Introduction
The ability of artificial intelligence (AI) to analyze data in real-time and improve patients’ diagnosis has led to a rapid growth of AI- health research in Uganda. Yet, there are no national guidelines on how to conduct AI-research in an ethical manner. Recent studies have reported that ethics committees lack resources, expertise and training to appropriately address the risks that may arise from AI health research. This study aimed to develop a guide for ethical review of the development of AI systems in health research in Uganda.
Methods
This study employed an exploratory qualitative approach between March – October 2024, involving 35 stakeholders in two public universities in Uganda. In-depth interviews were conducted with twelve members of ethics committees who had ever reviewed AI- protocols, six bioethicists, eight health researchers and nine members of AI-development teams. A thematic approach was used to interpret the results.
Results
Six themes emerged from this data including promoting social value and equity; ensuring participants and end-user autonomy and safety; addressing data acquisition, access and sharing gaps; ensuring responsible data use and data minimization; promoting responsible AI and fostering collaborative partnerships. Respondents opined that AI holds promise for improving health research. However, its successful implementation demands ethical considerations to minimize harm to participants and end-users.
Conclusion
Overall, respondents felt that developing a guide for ethics review of AI-research may minimize potential harms that could arise from using AI tools in research. We recommend training of ethics committees on key ethical considerations for development of responsible AI tools.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Artificial Intelligence - ethics
/ Biomedical Research - ethics
/ Consent
/ Datasets
/ Ethics
/ Feedback
/ Guide
/ Humans
/ R&D
/ Science
/ Software
/ Theory of Medicine/Bioethics
/ Uganda
