Journal Article

The Persistence of Self-injurious and Aggressive Behavior in Males with Fragile X Syndrome Over 8 Years: A Longitudinal Study of Prevalence and Predictive Risk Markers

Oliver, Chris, Crawford, Hayley, Karakatsani, Efthalia, Singla, Gursharan

2019

Overview

Self-injurious and aggressive behaviors are common in fragile X syndrome (FXS). However, little is known about the persistence of these behaviors and associated risk markers. We established the prevalence and persistence of self-injurious and aggressive behaviors over eight years in males with FXS, and associations with risk markers. Results showed 77% and 69% persistence rates for self-injurious and aggressive behavior, respectively. Baseline levels of repetitive behavior predicted persistent self-injurious behavior. Chronological age, impulsivity and overactivity were associated with persistent aggressive behavior but only impulsivity predicted persistence. This is the first study to document the persistence of self-injurious and aggressive behavior in FXS over the medium to long term and to identify behavioral risk markers that might facilitate targeted early intervention.

• Publisher: Springer US,Springer,Springer Nature B.V
• Subject: Adults / Age Differences / Aggression / Aggression - psychology / Aggressive behavior / Aggressiveness / Analysis / At Risk Persons / Autism Spectrum Disorders / Behavior / Behavior Patterns / Behavior Problems / Behavioral Science and Psychology / Child and School Psychology / Conceptual Tempo / Early Intervention / Female / Follow-Up Studies / Fragile X syndrome / Fragile X Syndrome - epidemiology / Genetic Disorders / Humans / Hyperactivity / Impulsive Behavior / Impulsivity / Incidence / Injuries / Intellectual disabilities / Intellectual Disability / Longitudinal Studies / Male / Males / Men / Neurosciences / Original Paper / Parents / Pediatrics / Persistence / Predictor Variables / Prevalence / Prevalence studies (Epidemiology) / Prospective Studies / Psychological aspects / Psychology / Public Health / Repetitive behaviour / Risk / Risk behavior / Risk factors / Self Destructive Behavior / Self injury / Self-Injurious Behavior - epidemiology / Self-Injurious Behavior - psychology / Surveys and Questionnaires