Journal Article

Seroprevalence Of SARS-COV-2 infection in asymptomatic indigenous from the largest Brazilian periurban area

Maymone Gonçalves, Crhistinne Cavalheiro, de Oliveira, Laís Albuquerque, Rossoni, Regina, Croda, Julio, Simionatto, Simone, Marques, Michele Ferreira, da Silva Ferreira, Tiago, Croda, Mariana Garcia, dos Santos, Paulo César Pereira, Campos, Gubio Soares, Leite Torres, Alex José, Oliveira da Silva, Bruna, dos Santos Barbosa, Marcelo, Marchioro, Silvana Beutinger, Sardi, Silvia Inês, Machado, Layla Oliveira Campos Leite, de Almeida, Gabriel Barroso, Alves Gomes, Marilia Maria

2023

Overview

This study assessed the seroprevalence of SARS-CoV-2 in 496 asymptomatic individuals from Mato Grosso do Sul, located in Dourados, the largest periurban indigenous area in Brazil, from January 25 to February 4, 2021. The volunteers participated before receiving their first dose of the CoronaVac inactivated vaccine. For screening, blood samples were collected and analyzed using SARS-CoV-2 rapid tests and the enzyme-linked immunosorbent assay (ELISA). We observed varying trends in total anti-SARS-CoV-2 antibodies across different variables. Seropositivity among the participants tested was 63.70% (316/496) using the rapid test and 52.82% (262/496) were positive using the ELISA method. The majority of participants identified with the Guarani-Kaiowá ethnic group, with 66.15% (217/328), and other ethnic groups with 58.84% (193/328). The median age of the subjects was 30.5 years, with 79.57% (261/328) being femaleThis research showed the elevated seroprevalence of SARS-CoV-2 antibodies in asymptomatic Brazilians. The findings indicate a high seropositivity rate among the asymptomatic indigenous population of Midwest Brazil. This underscores the overlooked status of these communities and underscores the need for targeted national initiatives that emphasize the protection of vulnerable ethnic groups in the fight against COVID-19.

• Publisher: Public Library of Science,Public Library of Science (PLoS)
• Subject: Adult / Analysis / Antibodies / Antibodies, Viral / Asymptomatic / Asymptomatic Infections - epidemiology / Brazil / Brazil - epidemiology / Control / COVID-19 / COVID-19 - epidemiology / COVID-19 vaccines / Disease transmission / Enzyme-linked immunosorbent assay / Enzymes / Epidemics / Ethnicity / Evaluation / Humans / Indigenous Peoples / Informed consent / Marginalized groups / Minority & ethnic groups / Mortality / Pandemics / Population / Primary care / Questionnaires / Ratios / Sample size / SARS-CoV-2 / Seroepidemiologic Studies / Serology / Severe acute respiratory syndrome coronavirus 2 / Software / South American People / Towns / Vaccines / Viral antibodies