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Type 1 diabetes
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Journal Article
Type 1 diabetes
2014
Overview
Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes has grown substantially, particularly with regard to disease prediction and heterogeneity, pancreatic pathology, and epidemiology. Technological improvements in insulin pumps and continuous glucose monitors help patients with type 1 diabetes manage the challenge of lifelong insulin administration. Agents that show promise for averting debilitating disease-associated complications have also been identified. However, despite broad organisational, intellectual, and fiscal investments, no means for preventing or curing type 1 diabetes exists, and, globally, the quality of diabetes management remains uneven. This Seminar discusses current progress in epidemiology, pathology, diagnosis, and treatment of type 1 diabetes, and prospects for an improved future for individuals with this disease.
Publisher
Elsevier Ltd,Elsevier,Elsevier Limited
Subject
/ Biological and medical sciences
/ Diabetes
/ Diabetes Mellitus, Type 1 - complications
/ Diabetes Mellitus, Type 1 - diagnosis
/ Diabetes Mellitus, Type 1 - epidemiology
/ Diabetes Mellitus, Type 1 - therapy
/ Diabetes. Impaired glucose tolerance
/ Endocrine pancreas. Apud cells (diseases)
/ Etiopathogenesis. Screening. Investigations. Target tissue resistance
/ Glucose
/ Humans
/ Hypoglycemic Agents - administration & dosage
/ Hypoglycemic Agents - therapeutic use
/ Insulin
/ Insulin - administration & dosage
/ Islets of Langerhans - pathology
/ Peptides
/ Studies
