Journal Article

Sarcopenia and sarcopenic obesity among community-dwelling Peruvian adults: A cross-sectional study

Witham, Miles D., Pollard, Suzanne L., Bernabé-Ortiz, Antonio, Flores-Flores, Oscar, Parodi, Jose F., Siddharthan, Trishul, Hurst, John R., Zevallos-Morales, Alejandro, Checkley, William, Runzer-Colmenares, Fernando M.

2024

Overview

Sarcopenia and sarcopenic obesity (SO) have emerged as significant contributors to negative health outcomes in the past decade. We aimed to estimate the prevalence of probable sarcopenia, sarcopenia, and SO in a community-dwelling population of 1151 adults aged ≥55 years in Lima, Peru. This cross-sectional study was conducted between 2018 and 2020. Sarcopenia was defined as the presence of low muscle strength (LMS) and low muscle mass (LMM) according to European (EWGSOP2), US (FNIH) and Asian (AWGS2) guidelines. We measured muscle strength by maximum handgrip strength and muscle mass using bioelectrical impedance analyzer. SO was defined as a body mass index ≥ 30 kg/m2 and sarcopenia. The study participants had a mean age of 66.2 years (SD 7.1), age range between 60 to 92 years old, of which 621 (53.9%) were men. Among the sample, 41.7% were classified as obese (BMI ≥30.0 kg/m²). The prevalence of probable sarcopenia was estimated to be 22.7% (95%CI: 20.3-25.1) using the EWGSOP2 criteria and 27.8% (95%CI: 25.2-30.4) using the AWGS2 criteria. Sarcopenia prevalence, assessed using skeletal muscle index (SMI), was 5.7% (95%CI: 4.4-7.1) according to EWGSOP2 and 8.3% (95%CI: 6.7-9.9) using AWGS2 criteria. The prevalence of sarcopenia based on the FNIH criteria was 18.1% (95%CI: 15.8-20.3). The prevalence of SO, considering different sarcopenia definitions, ranged from 0.8% (95%CI: 0.3-1.3) to 5.0% (95%CI: 3.8-6.3). Our findings reveal substantial variation in the prevalence of sarcopenia and SO, underscoring the necessity for context-specific cut-off values. Although the prevalence of SO was relatively low, this result may be underestimated. Furthermore, the consistently high proportion of probable sarcopenia and sarcopenia point to a substantial public health burden.

• Publisher: Public Library of Science,Public Library of Science (PLoS)
• Subject: Adult / Aged / Aged, 80 and over / Biology and Life Sciences / Care and treatment / Complications and side effects / Cross-Sectional Studies / Diagnosis / Female / Hand Strength - physiology / Health aspects / Humans / Independent Living / Male / Medical examination / Medicine and Health Sciences / Middle Aged / Muscles / Obesity / Obesity - complications / Obesity - epidemiology / People and Places / Peru - epidemiology / Prevalence / Research and Analysis Methods / Risk factors / Sarcopenia / Sarcopenia - epidemiology