Journal Article

Strategic vision for improving human health at The Forefront of Genomics

Solomon, Benjamin D., Gunter, Chris, Wise, Anastasia L., Hutter, Carolyn M., Wetterstrand, Kris A., Felsenfeld, Adam L., Kaufman, David J., Di Francesco, Valentina, Vasquez, Susan, Easter, Carla L., Graham, Bettie J., Ostrander, Elaine A., Mandich, Allison, Rodriguez, Laura Lyman, Green, Eric D., Kish, Britny J., Dayal, Jyoti Gupta, Pavan, William J., Phillippy, Adam M., Leja, Darryl, Manolio, Teri A., Gahl, William A., Wellington, Christopher R., Biesecker, Leslie G., Kastner, Daniel L., Brody, Lawrence C., Feingold, Elise A., Liu, Paul, Bonham, Vence L., Bates, Sarah A.

2020

Overview

Starting with the launch of the Human Genome Project three decades ago, and continuing after its completion in 2003, genomics has progressively come to have a central and catalytic role in basic and translational research. In addition, studies increasingly demonstrate how genomic information can be effectively used in clinical care. In the future, the anticipated advances in technology development, biological insights, and clinical applications (among others) will lead to more widespread integration of genomics into almost all areas of biomedical research, the adoption of genomics into mainstream medical and public-health practices, and an increasing relevance of genomics for everyday life. On behalf of the research community, the National Human Genome Research Institute recently completed a multi-year process of strategic engagement to identify future research priorities and opportunities in human genomics, with an emphasis on health applications. Here we describe the highest-priority elements envisioned for the cutting-edge of human genomics going forward—that is, at ‘The Forefront of Genomics’. In this Perspective, authors from the National Human Genome Research Institute (NHGRI) present a vision for human genomics research for the coming decade.

• Publisher: Nature Publishing Group UK,Nature Publishing Group
• Subject: 631/208/212 / 631/208/212/2301 / 692/308/2056 / 706/648/179 / Artificial intelligence / Biomedical research / Biomedical Research - economics / Biomedical Research - trends / COVID-19 - genetics / Genetic research / Genome, Human - genetics / Genomes / Genomics / Genomics - economics / Genomics - trends / Health aspects / Human genome / Human Genome Project / Humanities and Social Sciences / Humans / Medical research / multidisciplinary / National Human Genome Research Institute (U.S.) - economics / Perspective / Public health / Public Health - standards / Science / Science (multidisciplinary) / Social Change / Strategic planning / Translational Research, Biomedical - economics / Translational Research, Biomedical - trends / Underserved populations / United States / Values