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Revised Hammersmith Scale for spinal muscular atrophy: Inter and intra-rater reliability and agreement
by
Ramdharry, Gita
, Muntoni, Francesco
, Scoto, Mariacristina
, Wallace, Amanda
, Ramsey, Danielle
in
Agreements
/ Analysis
/ Atrophy
/ Biology and Life Sciences
/ Care and treatment
/ Child
/ Clinical trials
/ Computer and Information Sciences
/ Correlation coefficient
/ Correlation coefficients
/ Diagnosis
/ Engineering and Technology
/ Humans
/ Medicine and Health Sciences
/ Muscular Atrophy, Spinal - diagnosis
/ Neuromuscular diseases
/ Neurons
/ Observer Variation
/ Patients
/ Pediatrics
/ Physical Examination
/ Physical Therapists
/ Prospective Studies
/ Reliability analysis
/ Reproducibility of Results
/ Research and Analysis Methods
/ Social Sciences
/ Spinal muscular atrophy
/ Variability
2022
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Revised Hammersmith Scale for spinal muscular atrophy: Inter and intra-rater reliability and agreement
by
Ramdharry, Gita
, Muntoni, Francesco
, Scoto, Mariacristina
, Wallace, Amanda
, Ramsey, Danielle
in
Agreements
/ Analysis
/ Atrophy
/ Biology and Life Sciences
/ Care and treatment
/ Child
/ Clinical trials
/ Computer and Information Sciences
/ Correlation coefficient
/ Correlation coefficients
/ Diagnosis
/ Engineering and Technology
/ Humans
/ Medicine and Health Sciences
/ Muscular Atrophy, Spinal - diagnosis
/ Neuromuscular diseases
/ Neurons
/ Observer Variation
/ Patients
/ Pediatrics
/ Physical Examination
/ Physical Therapists
/ Prospective Studies
/ Reliability analysis
/ Reproducibility of Results
/ Research and Analysis Methods
/ Social Sciences
/ Spinal muscular atrophy
/ Variability
2022
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Revised Hammersmith Scale for spinal muscular atrophy: Inter and intra-rater reliability and agreement
by
Ramdharry, Gita
, Muntoni, Francesco
, Scoto, Mariacristina
, Wallace, Amanda
, Ramsey, Danielle
in
Agreements
/ Analysis
/ Atrophy
/ Biology and Life Sciences
/ Care and treatment
/ Child
/ Clinical trials
/ Computer and Information Sciences
/ Correlation coefficient
/ Correlation coefficients
/ Diagnosis
/ Engineering and Technology
/ Humans
/ Medicine and Health Sciences
/ Muscular Atrophy, Spinal - diagnosis
/ Neuromuscular diseases
/ Neurons
/ Observer Variation
/ Patients
/ Pediatrics
/ Physical Examination
/ Physical Therapists
/ Prospective Studies
/ Reliability analysis
/ Reproducibility of Results
/ Research and Analysis Methods
/ Social Sciences
/ Spinal muscular atrophy
/ Variability
2022
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Revised Hammersmith Scale for spinal muscular atrophy: Inter and intra-rater reliability and agreement
Journal Article
Revised Hammersmith Scale for spinal muscular atrophy: Inter and intra-rater reliability and agreement
2022
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Overview
The Revised Hammersmith Scale (RHS) for Spinal Muscular Atrophy (SMA) was designed as a psychometrically robust clinical outcome assessment to assess physical abilities of patients with type 2 and 3 SMA. The reliability properties of the RHS have not yet been reported. A prospective RHS reliability study was undertaken in a UK cohort of experienced neuromuscular paediatric Physiotherapists. Reliability testing was conducted via a virtual survey platform two weeks apart. Through the virtual platform participants scored videos of two RHS assessments, one of a child with SMA 2 and one of a child with SMA 3. Inter and intra-rater reliability was analysed using a type 3 Intraclass Correlation Coefficient (ICC). Intra-rater agreement was further analysed using Bland Altman (BA) Limits of Agreement (LOA) and plots. The acceptable inter and intra-rater variability was set as a change of ± 2 by the international team of expert physiotherapists who developed the RHS. Inter-rater agreement, n = 22 raters, type 3 ICC was 0.989 (95% CI 0.944 to 1.00), 97.7% of scores were within the acceptable limits of ± 2 points. Intra-rater agreement, n = 21 raters, type 3 ICC ranged from 0.922 to 1.0, with 97.6% of scores within the acceptable limits of ± 2 points. The mean SMA 2 intra-rater difference was -0.10 (-0.6 to 0.4), with lower LOA -2.24 and upper LOA +2.04. Intra-rater difference between tests for SMA 3 intra-rater difference was -0.05 (-0.6 to 0.5), with lower LOA -2.48 and upper LOA +2.38. Intra-rater scoring precision fell within BA agreement limits of ±2 points. The results demonstrate that the RHS is highly reliable when used by experienced UK physiotherapists, and variability of test scores regarding inter and intra-rater reliability was confirmed to lie within ±2 points.
Publisher
Public Library of Science,Public Library of Science (PLoS)
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