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Fecal Microbiota Transplantation for Severe Infant Botulism, China

by Jia, Xinlei , Gao, Hengmiao , Zhang, Bike , Qian, Suyun , Fan, Chaonan , Li, Rubo , Li, Kechun , Xu, Xuefang , Wang, Lijuan

in Amino acids / Antitoxins / Babies / Bile / Bioassays / Biological products / Botulism / Botulism - microbiology / Botulism - therapy / Care and treatment / Case studies / Children / Children & youth / China / Clostridium botulinum / Diseases / Fecal Microbiota Transplantation / Fecal Microbiota Transplantation for Severe Infant Botulism, China / Feces / Feces - microbiology / Food contamination / Gastrointestinal Microbiome / gut microbiome / Health aspects / Hospitalization / Hospitals / Humans / Infant / Infant botulism / Infants / Infants (Newborn) / Infectious diseases / Intensive care / Male / Metabolism / Metabolites / Microbiota / Microbiota (Symbiotic organisms) / Pediatrics / R&D / Research & development / Research Letter / Resveratrol / source-tracking / targeted metabolomics / Toxins / Treatment Outcome

2024

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Fecal Microbiota Transplantation for Severe Infant Botulism, China

by Jia, Xinlei , Gao, Hengmiao , Zhang, Bike , Qian, Suyun , Fan, Chaonan , Li, Rubo , Li, Kechun , Xu, Xuefang , Wang, Lijuan

2024

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Fecal Microbiota Transplantation for Severe Infant Botulism, China

by Jia, Xinlei , Gao, Hengmiao , Zhang, Bike , Qian, Suyun , Fan, Chaonan , Li, Rubo , Li, Kechun , Xu, Xuefang , Wang, Lijuan

2024

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Journal Article

Fecal Microbiota Transplantation for Severe Infant Botulism, China

Jia, Xinlei,

Gao, Hengmiao,

Zhang, Bike,

Qian, Suyun,

Fan, Chaonan,

Li, Rubo,

Li, Kechun,

Xu, Xuefang,

Wang, Lijuan

2024

Overview

Infant botulism in a 4-month-old boy in China who continued to excrete toxins for over a month despite antitoxin therapy was further treated with fecal microbiota transplantation. After treatment, we noted increased gut microbial diversity and altered fecal metabolites, which may help reduce intestinal pH and enhance anti-inflammatory capabilities.

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Publisher

U.S. National Center for Infectious Diseases,Centers for Disease Control and Prevention

Subject

Amino acids

/ Antitoxins

/ Babies

/ Bile

/ Bioassays

/ Biological products

/ Botulism