Journal Article

Understanding HIV Risk Behavior among Tuberculosis Patients with Alcohol Use Disorders in Tomsk, Russian Federation

Lastimoso, Charmaine S., Nelson, A. Katrina, Yanova, Galina, Livchits, Viktoria, Yanov, Sergei, Atwood, Sidney, Miller, Ann C., Connery, Hilary S., Shin, Sonya S., Greenfield, Shelly F.

2016

Overview

Russian Federation's (RF) HIV epidemic is the fastest growing of any country. This study explores factors associated with high HIV risk behavior in tuberculosis (TB) patients with alcohol use disorders in Tomsk, RF. This analysis was nested within the Integrated Management of Physician-delivered Alcohol Care for TB Patients (IMPACT, trial number NCT00675961) randomized controlled study of integrating alcohol treatment into TB treatment in Tomsk. Demographics, HIV risk behavior (defined as participant report of high-risk intravenous drug use and/or multiple sexual partners with inconsistent condom use in the last six months), clinical data, alcohol use, depression and psychosocial factors were collected from 196 participants (161 male and 35 female) at baseline. Forty-six participants (23.5%) endorsed HIV risk behavior at baseline. Incarceration history(Odds Ratio (OR)3.93, 95% confidence interval (CI) 1.95, 7.95), age under 41 (OR:2.97, CI:1.46, 6.04), drug addiction(OR: 3.60 CI:1.10, 11.77), history of a sexually transmitted disease(STD)(OR 2.00 CI:1.02, 3.90), low social capital (OR:2.81 CI:0.99, 8.03) and heavier alcohol use (OR:2.56 CI: 1.02, 6.46) were significantly more likely to be associated with HIV risk behavior at baseline. In adjusted analysis, age under 41(OR: 4.93, CI: 2.10, 11.58), incarceration history(OR: 3.56 CI:1.55, 8.17) and STD history (OR: 3.48, CI: 1.5, 8.10) continued to be significantly associated with HIV risk behavior. Understanding HIV transmission dynamics in Russia remains an urgent priority to inform strategies to address the epidemic. Larger studies addressing sex differences in risks and barriers to protective behavior are needed.

• Publisher: Public Library of Science,Public Library of Science (PLoS)
• Subject: Acquired immune deficiency syndrome / Addictive behaviors / Adult / AIDS / Alcohol use / Alcoholic beverages / Alcoholism - epidemiology / Alcoholism - psychology / Alcohols / Attitude to Health / Biology and Life Sciences / Care and treatment / Confidence intervals / Demographics / Demography / Disease transmission / Disorders / Drinking (Alcoholic beverages) / Drug abuse / Drug addiction / Drug use / Epidemics / Female / Gender aspects / Gender differences / Health aspects / Health risks / HIV / HIV Infections - prevention & control / Human immunodeficiency virus / Humans / Intravenous administration / Male / Marginalized groups / Medical diagnosis / Medicine and Health Sciences / Mental depression / Middle Aged / Patients / People and Places / Protective behavior / Risk factors / Risk taking / Russia - epidemiology / Sex differences / Sexual behavior / Sexual partners / Sexually transmitted diseases / Social Sciences / STD / Tuberculosis / Tuberculosis, Pulmonary - epidemiology / Tuberculosis, Pulmonary - psychology / Unsafe Sex