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Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan
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Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan
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Journal Article
Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan
2023
Overview
Pfhrp2 and pfhrp3 gene deletions threaten the use of Plasmodium falciparum malaria rapid diagnostic tests globally. In South Sudan, deletion frequencies were 15.6% for pfhrp2, 20.0% for pfhrp3, and 7.5% for double deletions. Deletions were approximately twice as prevalent in monoclonal infections than in polyclonal infections.
Publisher
U.S. National Center for Infectious Diseases,Centers for Disease Control and Prevention
Subject
/ and
/ Antigens, Protozoan - genetics
/ Control
/ Disease
/ Dispatch
/ Gene Deletions in Malaria-Hyperendemic Region, South Sudan
/ Genes
/ Humans
/ Malaria
/ Malaria, Falciparum - diagnosis
/ Malaria, Falciparum - epidemiology
/ Patients
/ Plasmodium falciparum - genetics
/ Proteins
/ Protozoan Proteins - genetics
/ RDT
