Asset Details
Do you wish to reserve the book?
Graphene Functionalized Scaffolds Reduce the Inflammatory Response and Supports Endogenous Neuroblast Migration when Implanted in the Adult Brain
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Graphene Functionalized Scaffolds Reduce the Inflammatory Response and Supports Endogenous Neuroblast Migration when Implanted in the Adult Brain
Do you wish to request the book?
Graphene Functionalized Scaffolds Reduce the Inflammatory Response and Supports Endogenous Neuroblast Migration when Implanted in the Adult Brain
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Graphene Functionalized Scaffolds Reduce the Inflammatory Response and Supports Endogenous Neuroblast Migration when Implanted in the Adult Brain
2016
Overview
Electroactive materials have been investigated as next-generation neuronal tissue engineering scaffolds to enhance neuronal regeneration and functional recovery after brain injury. Graphene, an emerging neuronal scaffold material with charge transfer properties, has shown promising results for neuronal cell survival and differentiation in vitro. In this in vivo work, electrospun microfiber scaffolds coated with self-assembled colloidal graphene, were implanted into the striatum or into the subventricular zone of adult rats. Microglia and astrocyte activation levels were suppressed with graphene functionalization. In addition, self-assembled graphene implants prevented glial scarring in the brain 7 weeks following implantation. Astrocyte guidance within the scaffold and redirection of neuroblasts from the subventricular zone along the implants was also demonstrated. These findings provide new functional evidence for the potential use of graphene scaffolds as a therapeutic platform to support central nervous system regeneration.
Publisher
Public Library of Science,Public Library of Science (PLoS)
Subject
/ Brain
/ Cell Movement - drug effects
/ Cicatrix - prevention & control
/ Coated Materials, Biocompatible - toxicity
/ Colloids
/ Corpus Striatum - physiology
/ Foreign-Body Reaction - etiology
/ Foreign-Body Reaction - prevention & control
/ Gliosis - prevention & control
/ Graphene
/ Graphite - administration & dosage
/ Lateral Ventricles - injuries
/ Lateral Ventricles - pathology
/ Lateral Ventricles - physiology
/ Male
/ Medicine and Health Sciences
/ Nanostructures - administration & dosage
/ Nanostructures - adverse effects
/ Nerve Regeneration - drug effects
/ Neural Stem Cells - cytology
/ Neurons
/ Prostheses and Implants - adverse effects
/ Rats
/ Rodents
/ Scars
