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Recent advances in diagnosis and management of Mycotic Keratitis

by Das, Sujata , Sharma, Namrata , Nagpal, Ritu , Maharana, Prafulla K , Jhanji, Vishal , Vajpayee, Rasik B

in Antifungal agents / Antifungal Agents - therapeutic use / Antimicrobial peptides / Care and treatment / Case reports / Caspofungin / Chemokines / Comparative analysis / Confocal microscopy / Cornea / Cornea - microbiology / Cornea - pathology / Diagnosis / Disease Management / Drug delivery systems / Drug therapy / Eye Infections, Fungal - diagnosis / Eye Infections, Fungal - drug therapy / Eye Infections, Fungal - microbiology / Fungal infections / fungal keratitis / Fungi / Gene expression / Humans / Immune response / Keratitis / Keratitis - diagnosis / Keratitis - drug therapy / Keratitis - microbiology / Methods / Microscopy / Microscopy, Confocal / Mycoses / mycotic keratitis / Neutrophils / Observations / Organisms / Peptides / polymerase chain reaction / posaconazole / Prognosis / Review / Review Article / Ribosomal DNA / Risk factors / Studies / voriconazole

2016

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Recent advances in diagnosis and management of Mycotic Keratitis

by Das, Sujata , Sharma, Namrata , Nagpal, Ritu , Maharana, Prafulla K , Jhanji, Vishal , Vajpayee, Rasik B

2016

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Recent advances in diagnosis and management of Mycotic Keratitis

by Das, Sujata , Sharma, Namrata , Nagpal, Ritu , Maharana, Prafulla K , Jhanji, Vishal , Vajpayee, Rasik B

2016

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Journal Article

Recent advances in diagnosis and management of Mycotic Keratitis

Das, Sujata,

Sharma, Namrata,

Nagpal, Ritu,

Maharana, Prafulla K,

Jhanji, Vishal,

Vajpayee, Rasik B

2016

Overview

Mycotic keratitis is a major cause of corneal blindness, especially in tropical and subtropical countries. The prognosis is markedly worse compared to bacterial keratitis. Delayed diagnosis and scarcity of effective antifungal agents are the major factors for poor outcome. Over the last decade, considerable progress has been made to rapidly diagnose cases with mycotic keratitis and increase the efficacy of treatment. This review article discusses the recent advances in diagnosis and management of mycotic keratitis with a brief discussion on rare and emerging organisms. A MEDLINE search was carried out for articles in English language, with the keywords, mycotic keratitis, fungal keratitis, emerging or atypical fungal pathogens in mycotic keratitis, investigations in mycotic keratitis, polymerase chain reaction in mycotic keratitis, confocal microscopy, treatment of mycotic keratitis, newer therapy for mycotic keratitis. All relevant articles were included in this review. Considering the limited studies available on newer diagnostic and therapeutic modalities in mycotic keratitis, case series as well as case reports were also included if felt important.

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Publisher

Wolters Kluwer - Medknow,Medknow Publications and Media Pvt. Ltd,Medknow Publications & Media Pvt. Ltd,Medknow Publications & Media Pvt Ltd,Wolters Kluwer Medknow Publications

Subject

Antifungal agents

/ Antifungal Agents - therapeutic use

/ Antimicrobial peptides

/ Comparative analysis

/ Confocal microscopy

/ Cornea

/ Cornea - microbiology