Journal Article

A Korean validation study of the Clinically Useful Anxiety Outcome Scale: Comorbidity and differentiation of anxiety and depressive disorders

Sang Won Jeon, Joonho Choi, Changsu Han, Chi-Un Pae, Young-Hoon Ko, Ho-Kyoung Yoon, Ashwin A. Patkar, Mark Zimmerman, Jae-Min Kim, Hoseon Lee, Seoyoung Yoon

2017

Overview

This study aimed to evaluate the psychometric properties of the Korean version of the Clinically Useful Anxiety Outcome Scale (CUXOS) and to examine the current diagnostic comorbidity and differential severity of anxiety symptoms between major depressive disorder (MDD) and anxiety disorders. In total, 838 psychiatric outpatients were analyzed at their intake appointment. Diagnostic characteristics were examined using the structured clinical interview from the DSM-IV because the DSM5 was not available at the start of the study. The CUXOS score was measured and compared with that of 3 clinician rating scales and 4 self-report scales. The CUXOS showed excellent results for internal consistency (Cronbach's α = 0.90), test-retest reliability (r = 0.74), and discriminant and convergent validity. The CUXOS significantly discriminated between different levels of anxiety severity, and the measure was sensitive to change after treatment. Approximately 45% of patients with MDD were additionally diagnosed with anxiety disorders while 55% of patients with anxiety disorders additionally reported an MDD. There was a significant difference in CUXOS scores between diagnostic categories (MDD only, anxiety only, both disorders, and no MDD or anxiety disorder). The CUXOS scores differed significantly between all categories of depression (major, minor, and non-depression) except for the comparison between minor depression and non-depression groups. The Korean version of the CUXOS is a reliable and valid measure of the severity of anxiety symptoms. The use of the CUXOS could broaden the understanding of coexisting and differentiating characteristics of anxiety and depression.

• Publisher: Public Library of Science (PLoS),Public Library of Science
• Subject: Adult / Aged / Anxiety / Anxiety - diagnosis / Anxiety - epidemiology / Anxiety - therapy / Anxiety Disorders / Anxiety Disorders - diagnosis / Anxiety Disorders - epidemiology / Anxiety Disorders - therapy / Balances (scales) / Biology and Life Sciences / Categories / Comorbidity / Consistency / Depression (Mood disorder) / Depressive Disorder / Depressive Disorder - diagnosis / Diagnosis, Differential / Diagnostic systems / Differentiation / Disorders / Female / Humans / Koreans / Male / Medical diagnosis / Medicine / Medicine and Health Sciences / Mental depression / Middle Aged / Outpatients / Patient outcomes / Patients / Prevalence / Psychological aspects / Psychological tests / Psychometrics / Psychometrics - methods / Q / Quantitative psychology / R / Reliability / Reproducibility of Results / Republic of Korea / Research Article / Science / Severity of Illness Index / Social Sciences / Treatment Outcome / Validation studies / Young Adult