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Review: Endocrine pathways to regulate calcium homeostasis around parturition and the prevention of hypocalcemia in periparturient dairy cows

by Hernandez, L L , Hernández-Castellano, L E , Bruckmaier, R M

in 25-Hydroxyvitamin D / Animal lactation / Animals / Bones / Calcitonin / Calcitriol / Calcium / Calcium homeostasis / Calcium, Dietary - metabolism / Cattle / Cattle Diseases - metabolism / Collagen / Dairy cattle / Dairy products / Endocrine system / Endocrine System - metabolism / Enzymes / Female / Homeostasis / Hormones / Hypocalcemia / Hypocalcemia - metabolism / Hypocalcemia - veterinary / Kidneys / Lactation / Mammals / mammary gland / Mammary Glands, Animal - metabolism / metabolic diseases / metabolism / Milk / Milk - metabolism / milk synthesis / mineral balance / Parathyroid / Parathyroid hormone / Parathyroid Hormone - metabolism / Parturition / Physiology / Pregnancy / Prolactin / Prolactin - metabolism / Serotonin / Serotonin - metabolism / transition period / Vitamin D

2020

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Review: Endocrine pathways to regulate calcium homeostasis around parturition and the prevention of hypocalcemia in periparturient dairy cows

by Hernandez, L L , Hernández-Castellano, L E , Bruckmaier, R M

2020

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Review: Endocrine pathways to regulate calcium homeostasis around parturition and the prevention of hypocalcemia in periparturient dairy cows

by Hernandez, L L , Hernández-Castellano, L E , Bruckmaier, R M

2020

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Journal Article

Review: Endocrine pathways to regulate calcium homeostasis around parturition and the prevention of hypocalcemia in periparturient dairy cows

Hernandez, L L,

Hernández-Castellano, L E,

Bruckmaier, R M

2020

Overview

Calcium homeostasis is crucial for the normal function of the organism. Parathyroid hormone, calcitriol and calcitonin play critical roles in the homeostatic regulation of calcium. Serotonin and prolactin have also been shown to be involved in the regulation of calcium homeostasis. In modern dairy cows, the endocrine pathways controlling calcium homeostasis during non-lactating and non-pregnant physiological states are unable to fully support the increased demand of calcium required for milk synthesis at the onset of lactation. This review describes different endocrine systems associated with the regulation of calcium homeostasis in mammalian species around parturition with special focus on dairy cows. Additionally, classic and novel strategies to reduce the incidence of hypocalcemia in parturient dairy cows are discussed.

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Publisher

Elsevier Limited,Elsevier

Subject

25-Hydroxyvitamin D

/ Animal lactation

/ Animals

/ Bones

/ Calcitonin

/ Calcitriol

/ Calcium