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Intestinal Protothecosis in a Patient with Chronic Mucocutaneous Candidiasis
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Intestinal Protothecosis in a Patient with Chronic Mucocutaneous Candidiasis
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Journal Article
Intestinal Protothecosis in a Patient with Chronic Mucocutaneous Candidiasis
1998
Overview
Prototheca species are ubiquitous, aerobic, unicellular algae that are considered a possible mutation of the green algae, genus Chorella. These organisms are found in a wide range of environmental sites such as slime flux of trees, collecting systems of domestic or municipal sewage, marine water, and soil. Protothecal infections are extremely rare in humans. Three major clinical syndromes of human protothecosis have been described: cutaneous and subcutaneous infections, a localized form involving the articular bursae, and a disseminated form occurring in immunocompromised hosts. We describe a patient with chronic mucocutaneous candidiasis (CMC) who developed intractable intestinal protothecosis, resistant to treatment with amphotericin B and itraconazole, that responded partially to IFN- gamma .
Publisher
The University of Chicago Press,University of Chicago Press
Subject
/ Amphotericin B - therapeutic use
/ Biological and medical sciences
/ Biopsy
/ Candida
/ Candidiasis, Chronic Mucocutaneous - complications
/ Candidiasis, Chronic Mucocutaneous - pathology
/ Chronic mucocutaneous candidiasis
/ Humans
/ Interferon-gamma - therapeutic use
/ Intestinal Diseases - complications
/ Intestinal Diseases - drug therapy
/ Intestinal Diseases - pathology
/ Itraconazole - therapeutic use
/ Male
