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Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy

Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy

by Makoto Honda , Ali Seifinejad , Corinne Pfister , Nicolas Chartrel , Anne Vassalli , Ling Shan , Roland Liblau , Andrea Agnoletto , David Frieser , Dogan Grepper , Yoan Arribat , Marie Picot , Mergim Ramosaj , Gert J. Lammers , Lee A. Garrett-Sinha , Christian Iseli , Francesca Amati , Sha Li , Marie-Laure Possovre , Rolf Fronczek , Mehdi Tafti

in Animals / b-cell differentiation / Biological Sciences / Cataplexy / Cataplexy/genetics / Corticotropin-Releasing Hormone / Corticotropin-Releasing Hormone/genetics / crh / dna methylation / Epigenesis / Epigenesis, Genetic / expression / factor-alpha / gene / gene silencing / Genetic / hcrt / hypocretin neurons / Hypothalamus / Hypothalamus/metabolism / Intracellular Signaling Peptides and Proteins / Intracellular Signaling Peptides and Proteins/metabolism / methylation / Mice / Mice; Animals; Orexins/metabolism; Cataplexy/genetics; Intracellular Signaling Peptides and Proteins/metabolism; Neuropeptides/metabolism; Narcolepsy/genetics; Hypothalamus/metabolism; Epigenesis, Genetic; Corticotropin-Releasing Hormone/genetics; Corticotropin-Releasing Hormone/metabolism; CRH; HCRT; QRFP; gene silencing; methylation / Narcolepsy / Narcolepsy/genetics / Neuropeptides / Neuropeptides/metabolism / orexin / Orexins / Orexins/metabolism / phenotype / promoter / QRFP / tumor-necrosis-factor

2023

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Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy

by Makoto Honda , Ali Seifinejad , Corinne Pfister , Nicolas Chartrel , Anne Vassalli , Ling Shan , Roland Liblau , Andrea Agnoletto , David Frieser , Dogan Grepper , Yoan Arribat , Marie Picot , Mergim Ramosaj , Gert J. Lammers , Lee A. Garrett-Sinha , Christian Iseli , Francesca Amati , Sha Li , Marie-Laure Possovre , Rolf Fronczek , Mehdi Tafti

in Animals / b-cell differentiation / Biological Sciences / Cataplexy / Cataplexy/genetics / Corticotropin-Releasing Hormone / Corticotropin-Releasing Hormone/genetics / crh / dna methylation / Epigenesis / Epigenesis, Genetic / expression / factor-alpha / gene / gene silencing / Genetic / hcrt / hypocretin neurons / Hypothalamus / Hypothalamus/metabolism / Intracellular Signaling Peptides and Proteins / Intracellular Signaling Peptides and Proteins/metabolism / methylation / Mice / Mice; Animals; Orexins/metabolism; Cataplexy/genetics; Intracellular Signaling Peptides and Proteins/metabolism; Neuropeptides/metabolism; Narcolepsy/genetics; Hypothalamus/metabolism; Epigenesis, Genetic; Corticotropin-Releasing Hormone/genetics; Corticotropin-Releasing Hormone/metabolism; CRH; HCRT; QRFP; gene silencing; methylation / Narcolepsy / Narcolepsy/genetics / Neuropeptides / Neuropeptides/metabolism / orexin / Orexins / Orexins/metabolism / phenotype / promoter / QRFP / tumor-necrosis-factor

2023

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Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy

Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy

by Makoto Honda , Ali Seifinejad , Corinne Pfister , Nicolas Chartrel , Anne Vassalli , Ling Shan , Roland Liblau , Andrea Agnoletto , David Frieser , Dogan Grepper , Yoan Arribat , Marie Picot , Mergim Ramosaj , Gert J. Lammers , Lee A. Garrett-Sinha , Christian Iseli , Francesca Amati , Sha Li , Marie-Laure Possovre , Rolf Fronczek , Mehdi Tafti

in Animals / b-cell differentiation / Biological Sciences / Cataplexy / Cataplexy/genetics / Corticotropin-Releasing Hormone / Corticotropin-Releasing Hormone/genetics / crh / dna methylation / Epigenesis / Epigenesis, Genetic / expression / factor-alpha / gene / gene silencing / Genetic / hcrt / hypocretin neurons / Hypothalamus / Hypothalamus/metabolism / Intracellular Signaling Peptides and Proteins / Intracellular Signaling Peptides and Proteins/metabolism / methylation / Mice / Mice; Animals; Orexins/metabolism; Cataplexy/genetics; Intracellular Signaling Peptides and Proteins/metabolism; Neuropeptides/metabolism; Narcolepsy/genetics; Hypothalamus/metabolism; Epigenesis, Genetic; Corticotropin-Releasing Hormone/genetics; Corticotropin-Releasing Hormone/metabolism; CRH; HCRT; QRFP; gene silencing; methylation / Narcolepsy / Narcolepsy/genetics / Neuropeptides / Neuropeptides/metabolism / orexin / Orexins / Orexins/metabolism / phenotype / promoter / QRFP / tumor-necrosis-factor

2023

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Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy

Journal Article

Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy

Makoto Honda,

Ali Seifinejad,

Corinne Pfister,

Nicolas Chartrel,

Anne Vassalli,

Ling Shan,

Roland Liblau,

Andrea Agnoletto,

David Frieser,

Dogan Grepper,

Yoan Arribat,

Marie Picot,

Mergim Ramosaj,

Gert J. Lammers,

Lee A. Garrett-Sinha,

Christian Iseli,

Francesca Amati,

Sha Li,

Marie-Laure Possovre,

Rolf Fronczek,

Mehdi Tafti

2023

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Publisher

Proceedings of the National Academy of Sciences

Subject

/ b-cell differentiation

/ Biological Sciences

/ Cataplexy/genetics

/ Corticotropin-Releasing Hormone

/ Corticotropin-Releasing Hormone/genetics

/ dna methylation

/ Epigenesis, Genetic

/ gene silencing

/ hypocretin neurons

/ Hypothalamus/metabolism

/ Intracellular Signaling Peptides and Proteins

/ Intracellular Signaling Peptides and Proteins/metabolism

/ Mice; Animals; Orexins/metabolism; Cataplexy/genetics; Intracellular Signaling Peptides and Proteins/metabolism; Neuropeptides/metabolism; Narcolepsy/genetics; Hypothalamus/metabolism; Epigenesis, Genetic; Corticotropin-Releasing Hormone/genetics; Corticotropin-Releasing Hormone/metabolism; CRH; HCRT; QRFP; gene silencing; methylation

/ Narcolepsy/genetics

/ Neuropeptides

/ Neuropeptides/metabolism

/ Orexins/metabolism

/ tumor-necrosis-factor

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