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Vulval fixed drug eruption following trimethoprim use
by
Tyagi-Bhatia, Jaya
, Chong, Kar Yan
in
Allergies
/ Anti-Bacterial Agents - adverse effects
/ Anti-Infective Agents, Urinary - adverse effects
/ Antibiotics
/ Antigens
/ Case reports
/ Consent
/ Diagnosis, Differential
/ Drug Eruptions - diagnosis
/ Drug Eruptions - drug therapy
/ Drug Eruptions - etiology
/ Drugs: obstetrics and gynaecology
/ Erythema
/ Female
/ Humans
/ Infections
/ Lymphocytes
/ Medical diagnosis
/ Obstetrics and gynaecology
/ Pain
/ Pathophysiology
/ Patients
/ Skin
/ Steroids
/ Trimethoprim - adverse effects
/ Trimethoprim, Sulfamethoxazole Drug Combination - adverse effects
/ Vulvar Diseases - chemically induced
/ Vulvovaginal disorders
/ Women
2025
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Vulval fixed drug eruption following trimethoprim use
by
Tyagi-Bhatia, Jaya
, Chong, Kar Yan
in
Allergies
/ Anti-Bacterial Agents - adverse effects
/ Anti-Infective Agents, Urinary - adverse effects
/ Antibiotics
/ Antigens
/ Case reports
/ Consent
/ Diagnosis, Differential
/ Drug Eruptions - diagnosis
/ Drug Eruptions - drug therapy
/ Drug Eruptions - etiology
/ Drugs: obstetrics and gynaecology
/ Erythema
/ Female
/ Humans
/ Infections
/ Lymphocytes
/ Medical diagnosis
/ Obstetrics and gynaecology
/ Pain
/ Pathophysiology
/ Patients
/ Skin
/ Steroids
/ Trimethoprim - adverse effects
/ Trimethoprim, Sulfamethoxazole Drug Combination - adverse effects
/ Vulvar Diseases - chemically induced
/ Vulvovaginal disorders
/ Women
2025
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Vulval fixed drug eruption following trimethoprim use
by
Tyagi-Bhatia, Jaya
, Chong, Kar Yan
in
Allergies
/ Anti-Bacterial Agents - adverse effects
/ Anti-Infective Agents, Urinary - adverse effects
/ Antibiotics
/ Antigens
/ Case reports
/ Consent
/ Diagnosis, Differential
/ Drug Eruptions - diagnosis
/ Drug Eruptions - drug therapy
/ Drug Eruptions - etiology
/ Drugs: obstetrics and gynaecology
/ Erythema
/ Female
/ Humans
/ Infections
/ Lymphocytes
/ Medical diagnosis
/ Obstetrics and gynaecology
/ Pain
/ Pathophysiology
/ Patients
/ Skin
/ Steroids
/ Trimethoprim - adverse effects
/ Trimethoprim, Sulfamethoxazole Drug Combination - adverse effects
/ Vulvar Diseases - chemically induced
/ Vulvovaginal disorders
/ Women
2025
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Journal Article
Vulval fixed drug eruption following trimethoprim use
2025
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Overview
This case report describes an uncommon case of a woman who developed fixed drug eruption (FDE) on her vulval area secondary to trimethoprim use. She had no known history of drug allergy. Some common culprit medications that cause FDE include antimicrobials such as co-trimoxazole and non-steroidal anti-inflammatory agents. Vulval FDE is uncommon and should remain as an important differential diagnosis in women presenting with severe vulval pain accompanied by erythema and swelling, particularly after the introduction of a new medication. Discontinuation of trimethoprim along with the adjunct use of a steroid cream led to complete resolution of the patient’s symptoms.
Publisher
BMJ Publishing Group Ltd,BMJ Publishing Group LTD
Subject
/ Anti-Bacterial Agents - adverse effects
/ Anti-Infective Agents, Urinary - adverse effects
/ Antigens
/ Consent
/ Drug Eruptions - drug therapy
/ Drugs: obstetrics and gynaecology
/ Erythema
/ Female
/ Humans
/ Pain
/ Patients
/ Skin
/ Steroids
/ Trimethoprim - adverse effects
/ Trimethoprim, Sulfamethoxazole Drug Combination - adverse effects
/ Vulvar Diseases - chemically induced
/ Women
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