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Personal protective effect of wearing surgical face masks in public spaces on self-reported respiratory symptoms in adults: pragmatic randomised superiority trial
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Personal protective effect of wearing surgical face masks in public spaces on self-reported respiratory symptoms in adults: pragmatic randomised superiority trial
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Personal protective effect of wearing surgical face masks in public spaces on self-reported respiratory symptoms in adults: pragmatic randomised superiority trial
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Journal Article
Personal protective effect of wearing surgical face masks in public spaces on self-reported respiratory symptoms in adults: pragmatic randomised superiority trial
2024
Overview
AbstractObjectiveTo evaluate the personal protective effects of wearing versus not wearing surgical face masks in public spaces on self-reported respiratory symptoms over a 14 day period.DesignPragmatic randomised superiority trial.SettingNorway.Participants4647 adults aged ≥18 years: 2371 were assigned to the intervention arm and 2276 to the control arm.InterventionsParticipants in the intervention arm were assigned to wear a surgical face mask in public spaces (eg, shopping centres, streets, public transport) over a 14 day period (mask wearing at home or work was not mentioned). Participants in the control arm were assigned to not wear a surgical face mask in public places.Main outcome measuresThe primary outcome was self-reported respiratory symptoms consistent with a respiratory infection. Secondary outcomes included self-reported and registered covid-19 infection and self-reported sick leave.ResultsBetween 10 February 2023 and 27 April 2023, 4647 participants were randomised of whom 4575 (2788 women (60.9%); mean age 51.0 (standard deviation 15.0) years) were included in the intention-to-treat analysis: 2313 (50.6%) in the intervention arm and 2262 (49.4%) in the control arm. 163 events (8.9%) of self-reported symptoms consistent with respiratory infection were reported in the intervention arm and 239 (12.2%) in the control arm. The marginal odds ratio was 0.71 (95% confidence interval (CI) 0.58 to 0.87; P=0.001) favouring the face mask intervention. The absolute risk difference was −3.2% (95% CI −5.2% to −1.3%; P<0.001). No statistically significant effect was found on self- reported (marginal odds ratio 1.07, 95% CI 0.58 to 1.98; P=0.82) or registered covid-19 infection (effect estimate and 95% CI not estimable owing to lack of events in the intervention arm). Self-reported sick leave was equally distributed between the intervention and control groups (marginal odds ratio 1.00, 0.81 to 1.22; P=0.97).ConclusionWearing a surgical face mask in public spaces over 14 days reduces the risk of self-reported symptoms consistent with a respiratory infection, compared with not wearing a surgical face mask.Trial registrationClinicalTrials.gov NCT05690516.
Publisher
British Medical Journal Publishing Group,BMJ Publishing Group LTD
Subject
/ Aged
/ Consent
/ Coronavirus Infections - epidemiology
/ Coronavirus Infections - prevention & control
/ Coronavirus Infections - transmission
/ COVID-19
/ COVID-19 - prevention & control
/ Face
/ Female
/ Humans
/ Male
/ Masks
/ Pandemics - prevention & control
/ Pharmacy
/ Pneumonia, Viral - epidemiology
/ Pneumonia, Viral - prevention & control
/ Pneumonia, Viral - transmission
/ Respiratory Tract Infections - prevention & control
/ Surgery
