Asset Details
Do you wish to reserve the book?
Effect of “collaborative requesting” on consent rate for organ donation: randomised controlled trial (ACRE trial)
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Effect of “collaborative requesting” on consent rate for organ donation: randomised controlled trial (ACRE trial)
Do you wish to request the book?
Effect of “collaborative requesting” on consent rate for organ donation: randomised controlled trial (ACRE trial)
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Effect of “collaborative requesting” on consent rate for organ donation: randomised controlled trial (ACRE trial)
2009
Overview
Objective To determine whether collaborative requesting increases consent for organ donation from the relatives of patients declared dead by criteria for brain stem death.Design Unblinded multicentre randomised controlled trial using a sequential design. Centralised 24 hour telephone randomisation based on randomised permuted blocks of 10.Setting 79 general, neuroscience, and paediatric intensive care units in the United Kingdom.Participants 201 relatives of patients meeting criteria for brain stem death. Relatives were blind to the intervention and to the trial; all other participants were necessarily unblinded.Interventions Collaborative requesting for consent for organ donation by the potential donor’s clinician and a donor transplant coordinator (organ procurement officer) compared with routine requesting by the clinical team alone.Main outcome measure Proportion of relatives consenting to organ donation.Results 101 relatives were randomised to routine requesting and 100 to collaborative requesting. All were analysed on an intention to treat basis. In the routine requesting group, 62 relatives consented to organ donation. In the collaborative requesting group, 57 relatives consented. After correction for the ethnicity, age, and sex of the potential donors the risk adjusted ratio of the odds of consent in the collaborative requesting group relative to the routine group was 0.80 (95% confidence interval 0.43 to 1.53), with a P value of 0.49 adjusted for interim analysis and trial over-running. The conversion rate (donors with consent from whom any organs were retrieved) was 92% (57/62) in the routine requesting group and 79% (45/57) in the collaborative requesting group (P=0.043). There were 140 approaches to relatives in the per protocol analysis, leading to 60.3% (44/73) consent after routine and 67.2% (45/67) after collaborative requesting (risk adjusted odds ratio of consent 1.47, 0.67 to 3.20, P=0.33).Conclusion There is no increase in consent rates for organ donation when collaborative requesting is used in place of routine requesting by the patient’s clinician.Trial registration ISRCTN01169903
Publisher
British Medical Journal Publishing Group,British Medical Association,BMJ Publishing Group LTD,BMJ Publishing Group Ltd
