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Simple, Effective, but Out of Reach? Public Health Implications of HCV Drugs
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Simple, Effective, but Out of Reach? Public Health Implications of HCV Drugs
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Journal Article
Simple, Effective, but Out of Reach? Public Health Implications of HCV Drugs
2015
Overview
The results of four clinical trials showing the excellent safety and efficacy of a 12-week course of sofosbuvir (an NS5B inhibitor licensed in the United States in 2013) and velpatasvir (a new NS5A inhibitor) in treating patients with hepatitis C infection (HCV) are reported now in the
Journal
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In two of these studies, ASTRAL-1 and ASTRAL-2, 97 to 100% of patients with HCV genotype 1a, 1b, 2, 4, 5, or 6 had a sustained virologic response at 12 weeks after the end of therapy, a marker that is indicative of virologic cure. Similar efficacy was observed among patients . . .
Publisher
Massachusetts Medical Society
