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Age- and gender-dependent impact of titanium vertebral augmentation implants combined with cementing on subsequent vertebral fracture incidence: A comparative study with cementing alone
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Age- and gender-dependent impact of titanium vertebral augmentation implants combined with cementing on subsequent vertebral fracture incidence: A comparative study with cementing alone
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Age- and gender-dependent impact of titanium vertebral augmentation implants combined with cementing on subsequent vertebral fracture incidence: A comparative study with cementing alone
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Journal Article
Age- and gender-dependent impact of titanium vertebral augmentation implants combined with cementing on subsequent vertebral fracture incidence: A comparative study with cementing alone
2024
Overview
Purpose
To compare vertebroplasty (VP) and kyphoplasty (KP) with a titanium implantable vertebral augmentation device (TIVAD) in symptomatic subsequent vertebral compression fracture (SVCF) incidence among osteoporotic vertebral compression fracture (OVCF) patients stratified by age and sex.
Methods
This retrospective cohort study involved OVCF patients aged ≥ 50, who underwent KP with TIVAD or VP in our hospital from 2014 to 2019. Subgroup analysis was conducted to evaluate the efficacy of KP with TIVAD and VP in patients stratified by age and sex.
Results
The study included 472 patients (VP group: 303; TIVAD group: 169). SVCF incidence rates were 15.2% for VP group and 14.8% for TIVAD group (
P
= 0.87). In subgroup analysis, TIVAD group showed significantly lower SVCF incidence than VP group in women aged 50–70 (2.1% vs 14.3%;
P
= 0.03) and had significantly higher SVCF incidence than VP group in women aged > 70 (24.2% vs 13.1%;
P
= 0.02). In men, adjacent SVCF incidence was significantly lower in TIVAD group than VP group (0% vs 14.1%;
P
= 0.03).
Conclusion
Compared to VP, TIVAD is associated with lower symptomatic SVCF rate in men and younger women aged 50–70 but not in older women aged > 70. Age and gender may influence SVCF incidence.
Level of evidence
Diagnostic: individual cross-sectional studies with consistently applied reference standard and blinding.
Publisher
Springer Berlin Heidelberg,Springer Nature B.V
Subject
/ Aged
/ Female
/ Fractures, Compression - epidemiology
/ Fractures, Compression - surgery
/ Gender
/ Humans
/ Kyphoplasty - adverse effects
/ Male
/ Medicine
/ Osteoporotic Fractures - epidemiology
/ Osteoporotic Fractures - surgery
/ Patients
/ Prostheses and Implants - adverse effects
/ Spinal Fractures - epidemiology
/ Surgery
/ Titanium
