Journal Article

Computer-aided designed, three dimensional-printed hemipelvic prosthesis for peri-acetabular malignant bone tumour

Pu, Feifei, Hao, Yongqiang, Shao, Zengwu, Wang, Baichuan, Jiang, Wenbo

2018

Overview

Background Prosthetic reconstruction may be a promising treatment for peri-acetabular malignant bone tumour; however, it is associated with a high complication rate. Therefore, prosthetic design and approach of prosthetic reconstruction after tumour resection warrant study. Methods We retrospectively analyzed 11 patients with peri-acetabular malignant bone tumours treated by personalized 3D-printed hemipelvic prostheses after en bloc resection between 2015 and 2016. Pre-operative and post-operative pain at rest was assessed according to a 10-cm VAS score. The results of functional improvement were evaluated using the MSTS-93 score at the final follow-up. We also analyzed tumour recurrence, metastases, and complications associated with the reconstruction procedure. Results All patients were observed for six to 24 months with an average follow-up of 15.5 months. One patient had occasional pain of the involved hip at the final follow-up (VAS, pre vs. post 8 months: 3 vs. 2). The mean MSTS-93 score was 19.2 (range, 13–25). Hip dislocation was detected in two patients, while delayed wound healing occurred in one patient. One patient with mesenchymal chondrosarcoma had a left iliac bone metastasis. Local tumour recurrence was not observed. Conclusions Reconstruction of bony defect after tumour resection using personalized 3D-printed hemipelvic prostheses can obtain acceptable functional results without severe complications. Based on previous reports and our results, we believe that reconstruction arthroplasty using 3D-printed hemipelvic prostheses will provide a promising alternative for those patients with peri-acetabular malignant bone tumours. Level of Evidence : Level IV, therapeutic study.

• Publisher: Springer Berlin Heidelberg,Springer Nature B.V
• Subject: 3-D printers / Acetabulum - diagnostic imaging / Acetabulum - surgery / Adult / Arthroplasty - instrumentation / Arthroplasty - methods / Biopsy / Bone cancer / Bone Neoplasms - diagnostic imaging / Bone Neoplasms - surgery / Breast cancer / Cancer therapies / Chemotherapy / Computer-Aided Design / Design / Embolization / Female / Females / Humans / Joint surgery / Magnetic Resonance Imaging / Male / Medical prognosis / Medicine / Medicine & Public Health / Metastasis / Middle Aged / Original Paper / Orthopedics / Patients / Pelvic Bones - diagnostic imaging / Pelvic Bones - surgery / Pelvis / Printing, Three-Dimensional / Prostheses / Prostheses and Implants / Prosthesis Design / Prosthesis Implantation / Reconstructive Surgical Procedures - instrumentation / Reconstructive Surgical Procedures - methods / Retrospective Studies / Surgical techniques / Titanium alloys / Tomography / Tomography, X-Ray Computed / Tumors / Young Adult