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Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus

by Donders, Rogier , Derriks, Frank , Hundscheid, Tim , Hocq, Catheline , Onland, Wes , Nuytemans, Debbie H.G.M. , Zecic, Alexandra , Visser, Remco , Vijlbrief, Daniel C. , Dijk, Peter H. , Kroon, André A. , Villamor, Eduardo , Mulder-de Tollenaer, Susanne M. , van Kaam, Anton H. , de Boode, Willem P. , De Bisschop, Barbara , Mulder, Antonius L. , Kyng, Kasper J. , Henriksen, Tine B. , de Vries, Willem B. , de Baat, Tessa , Kooi, Elisabeth M.W. , Van Overmeire, Bart , Dijkman, Koen P. , Meeus, Marisse , Avino, Daniela

in Age / Birth weight / Bronchopulmonary Dysplasia - etiology / Cardiology / Cardiology General / Clinical outcomes / Confidence intervals / Congenital diseases / Congenital Heart Disease / Consent / Coronary vessels / Death / Disease management / Ductus Arteriosus, Patent - diagnostic imaging / Ductus Arteriosus, Patent - drug therapy / Ductus Arteriosus, Patent - mortality / Ductus Arteriosus, Patent - therapy / Dysplasia / Echocardiography / Enterocolitis, Necrotizing - etiology / Gestational age / Humans / Hypothesis testing / Ibuprofen / Ibuprofen - administration & dosage / Ibuprofen - adverse effects / Ibuprofen - therapeutic use / Indomethacin - adverse effects / Indomethacin - therapeutic use / Infant / Infant, Extremely Premature / Infant, Low Birth Weight / Infant, Newborn / Infant, Newborn, Diseases - drug therapy / Infant, Newborn, Diseases - therapy / Infants / Intensive care / Lung diseases / Morbidity / Mortality / Necrotizing enterocolitis / Neonatology / Newborn babies / Nonsteroidal anti-inflammatory drugs / Pediatrics / Premature babies / Prostaglandin endoperoxide synthase / Pulmonary arteries / Statistical analysis / Watchful Waiting

2023

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2023

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2023

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Journal Article

Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus

Donders, Rogier,

Derriks, Frank,

Hundscheid, Tim,

Hocq, Catheline,

Onland, Wes,

Nuytemans, Debbie H.G.M.,

Zecic, Alexandra,

Visser, Remco,

Vijlbrief, Daniel C.,

Dijk, Peter H.,

Kroon, André A.,

Villamor, Eduardo,

Mulder-de Tollenaer, Susanne M.,

van Kaam, Anton H.,

de Boode, Willem P.,

De Bisschop, Barbara,

Mulder, Antonius L.,

Kyng, Kasper J.,

Henriksen, Tine B.,

de Vries, Willem B.,

de Baat, Tessa,

Kooi, Elisabeth M.W.,

Van Overmeire, Bart,

Dijkman, Koen P.,

Meeus, Marisse,

Avino, Daniela

2023

Overview

In preterm infants with patent ductus arteriosus, expectant management was noninferior to ibuprofen therapy with respect to necrotizing enterocolitis, bronchopulmonary dysplasia, or death at 36 weeks.

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Publisher

Massachusetts Medical Society

Subject

Age

/ Birth weight

/ Bronchopulmonary Dysplasia - etiology

/ Cardiology

/ Cardiology General

/ Clinical outcomes

/ Confidence intervals