Journal Article

EEG and fMRI evidence for autobiographical memory reactivation in empathy

Hanslmayr, Simon, S. Ferreira, Catarina, Michelmann, Sebastian, Staresina, Bernhard, Linde‐Domingo, Juan, Meconi, Federica, Apperly, Ian A.

2021

Overview

Empathy relies on the ability to mirror and to explicitly infer others' inner states. Theoretical accounts suggest that memories play a role in empathy, but direct evidence of reactivation of autobiographical memories (AM) in empathy is yet to be shown. We addressed this question in two experiments. In Experiment 1, electrophysiological activity (EEG) was recorded from 28 participants. Participants performed an empathy task in which targets for empathy were depicted in contexts for which participants either did or did not have an AM, followed by a task that explicitly required memory retrieval of the AM and non‐AM contexts. The retrieval task was implemented to extract the neural fingerprints of AM and non‐AM contexts, which were then used to probe data from the empathy task. An EEG pattern classifier was trained and tested across tasks and showed evidence for AM reactivation when participants were preparing their judgement in the empathy task. Participants self‐reported higher empathy for people depicted in situations they had experienced themselves as compared to situations they had not experienced. A second independent fMRI experiment replicated this behavioural finding and showed increased activation for AM compared to non‐AM in the brain networks underlying empathy: precuneus, posterior parietal cortex, superior and inferior parietal lobule, and superior frontal gyrus. Together, our study reports behavioural, electrophysiological, and fMRI evidence that robustly supports AM reactivation in empathy. Theoretical accounts suggest that memories play a role in empathy, but direct evidence of reactivation of autobiographical memories (AM) in empathy is yet to be shown. We addressed this question in one EEG and one fMRI experiment. Participants self‐reported higher empathy for people depicted in situations they had experienced themselves as compared to situations they had not experienced. An EEG pattern classifier showed evidence for AM reactivation when participants were preparing their judgement in the empathy task. Increased activation was observed for AM compared to non‐AM in the brain networks underlying empathy. Together, our study reports behavioural, electrophysiological, and fMRI evidence that robustly supports AM reactivation in empathy.

• Publisher: John Wiley & Sons, Inc
• Subject: Adult / Alzheimer's disease / autobiographical memory / Brain mapping / Cerebral Cortex - diagnostic imaging / Cerebral Cortex - physiology / Cognition & reasoning / Cortex (parietal) / Discriminant analysis / EEG / EEG pattern classifier / Electroencephalography - methods / Emotions / Empathy / Empathy - physiology / Experiments / Female / fMRI / Frontal gyrus / Functional magnetic resonance imaging / Functional Neuroimaging - methods / Humans / Magnetic Resonance Imaging - methods / Male / Medical imaging / Memory / Memory, Episodic / Mental Recall - physiology / Mental task performance / Neuropsychology / Pain / Retrieval / Semantics / Young Adult