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A physiologic comparison of proportional assist ventilation with load-adjustable gain factors (PAV+) versus pressure support ventilation (PSV)
by
Costa, R.
, Festa, O.
, Conti, G.
, Antonelli, M.
, Spinazzola, G.
, Cipriani, F.
, Arcangeli, A.
, Ferrone, G.
, Proietti, R.
in
Aged
/ Aged, 80 and over
/ Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
/ Anesthesiology
/ Biological and medical sciences
/ Body mass index
/ Chronic obstructive pulmonary disease
/ Critical Care Medicine
/ Emergency and intensive respiratory care
/ Emergency Medicine
/ Female
/ Humans
/ Intensive
/ Intensive care
/ Intensive care medicine
/ Interactive Ventilatory Support - standards
/ Male
/ Mechanics
/ Medical sciences
/ Medicine
/ Medicine & Public Health
/ Original
/ Pain Medicine
/ Patients
/ Pediatrics
/ Pneumology/Respiratory System
/ Pneumonia
/ Positive-Pressure Respiration - standards
/ Respiratory Mechanics - physiology
/ Rome
/ Tidal Volume - physiology
/ Ventilators
/ Ventilators, Negative-Pressure
/ Weaning
/ Work of Breathing - physiology
2011
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A physiologic comparison of proportional assist ventilation with load-adjustable gain factors (PAV+) versus pressure support ventilation (PSV)
by
Costa, R.
, Festa, O.
, Conti, G.
, Antonelli, M.
, Spinazzola, G.
, Cipriani, F.
, Arcangeli, A.
, Ferrone, G.
, Proietti, R.
in
Aged
/ Aged, 80 and over
/ Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
/ Anesthesiology
/ Biological and medical sciences
/ Body mass index
/ Chronic obstructive pulmonary disease
/ Critical Care Medicine
/ Emergency and intensive respiratory care
/ Emergency Medicine
/ Female
/ Humans
/ Intensive
/ Intensive care
/ Intensive care medicine
/ Interactive Ventilatory Support - standards
/ Male
/ Mechanics
/ Medical sciences
/ Medicine
/ Medicine & Public Health
/ Original
/ Pain Medicine
/ Patients
/ Pediatrics
/ Pneumology/Respiratory System
/ Pneumonia
/ Positive-Pressure Respiration - standards
/ Respiratory Mechanics - physiology
/ Rome
/ Tidal Volume - physiology
/ Ventilators
/ Ventilators, Negative-Pressure
/ Weaning
/ Work of Breathing - physiology
2011
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A physiologic comparison of proportional assist ventilation with load-adjustable gain factors (PAV+) versus pressure support ventilation (PSV)
by
Costa, R.
, Festa, O.
, Conti, G.
, Antonelli, M.
, Spinazzola, G.
, Cipriani, F.
, Arcangeli, A.
, Ferrone, G.
, Proietti, R.
in
Aged
/ Aged, 80 and over
/ Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
/ Anesthesiology
/ Biological and medical sciences
/ Body mass index
/ Chronic obstructive pulmonary disease
/ Critical Care Medicine
/ Emergency and intensive respiratory care
/ Emergency Medicine
/ Female
/ Humans
/ Intensive
/ Intensive care
/ Intensive care medicine
/ Interactive Ventilatory Support - standards
/ Male
/ Mechanics
/ Medical sciences
/ Medicine
/ Medicine & Public Health
/ Original
/ Pain Medicine
/ Patients
/ Pediatrics
/ Pneumology/Respiratory System
/ Pneumonia
/ Positive-Pressure Respiration - standards
/ Respiratory Mechanics - physiology
/ Rome
/ Tidal Volume - physiology
/ Ventilators
/ Ventilators, Negative-Pressure
/ Weaning
/ Work of Breathing - physiology
2011
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A physiologic comparison of proportional assist ventilation with load-adjustable gain factors (PAV+) versus pressure support ventilation (PSV)
Journal Article
A physiologic comparison of proportional assist ventilation with load-adjustable gain factors (PAV+) versus pressure support ventilation (PSV)
2011
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Overview
Purpose
To compare patient–ventilator interaction during PSV and PAV+ in patients that are difficult to wean.
Methods
This was a physiologic study involving 11 patients. During three consecutive trials (PSV first trial—PSV1, followed by PAV+, followed by a second PSV trial—PSV2, with the same settings as PSV1) we evaluated mechanical and patient respiratory pattern; inspiratory effort from excursion Pdi (swing
Pdi
), and pressure–time products of the transdiaphragmatic (PTPdi) pressures. Inspiratory (delay
trinsp
) and expiratory (delay
trexp
) trigger delays, time of synchrony (time
syn
), and asynchrony index (AI) were assessed.
Results
Compared to PAV+, during PSV trials, the mechanical inspiratory time (Ti
flow
) was significantly longer than patient inspiratory time (Ti
pat
) (
p
< 0.05); Ti
pat
showed a prolongation between PSV1 and PAV+, significant comparing PAV+ and PSV2 (
p
< 0.05). PAV+ significantly reduced delay
trexp
(
p
< 0.001). The portion of tidal volume (VT) delivered in phase with Ti
pat
(VT
pat
/VT
mecc
) was significantly higher during PAV+ (
p
< 0.01). The time of synchrony was significantly longer during PAV+ than during PSV (
p
< 0.001). During PSV 5 patients out of 11 showed an AI greater than 10%, whereas the AI was nil during PAV+.
Conclusion
PAV+ improves patient–ventilator interaction, significantly reducing the incidence of end-expiratory asynchrony and increasing the time of synchrony.
Publisher
Springer-Verlag,Springer,Springer Nature B.V
Subject
/ Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
/ Biological and medical sciences
/ Chronic obstructive pulmonary disease
/ Emergency and intensive respiratory care
/ Female
/ Humans
/ Interactive Ventilatory Support - standards
/ Male
/ Medicine
/ Original
/ Patients
/ Pneumology/Respiratory System
/ Positive-Pressure Respiration - standards
/ Respiratory Mechanics - physiology
/ Rome
/ Ventilators, Negative-Pressure
/ Weaning
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