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Transcatheter Aortic-Valve Replacement with a Self-Expanding Prosthesis

by Petrossian, George , Conte, John , Hughes, G. Chad , Zorn, George , Coselli, Joseph S , Gleason, Thomas G , Harrison, J. Kevin , Reardon, Michael J , Popma, Jeffrey J , Oh, Jae K , Kleiman, Neal S , Mumtaz, Mubashir , Robinson, Newell , Buchbinder, Maurice , Heiser, John , Adams, David H , Tadros, Peter , Merhi, William , Yakubov, Steven J , Deeb, G. Michael , Chetcuti, Stan , Hermiller, James , Chenoweth, Sharla , Maini, Brijeshwar

in Aged / Aged, 80 and over / Aortic stenosis / Aortic Valve - surgery / Aortic Valve Stenosis - mortality / Aortic Valve Stenosis - surgery / Aortic Valve Stenosis - therapy / Biological and medical sciences / Bioprosthesis / Cardiac Catheterization - adverse effects / Cardiology / Cerebrovascular system / Coronary vessels / Death / Female / General aspects / Heart surgery / Heart Valve Prosthesis / Humans / Kaplan-Meier Estimate / Male / Medical prognosis / Medical sciences / Mortality / Motivation / Postoperative Complications / Prostheses / Prosthesis Design / Quality of life / Risk assessment / Risk Factors / Stenosis / Stroke / Surgery / Survival Rate / Thorax

2014

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Transcatheter Aortic-Valve Replacement with a Self-Expanding Prosthesis

2014

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Transcatheter Aortic-Valve Replacement with a Self-Expanding Prosthesis

2014

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Journal Article

Transcatheter Aortic-Valve Replacement with a Self-Expanding Prosthesis

Petrossian, George,

Conte, John,

Hughes, G. Chad,

Zorn, George,

Coselli, Joseph S,

Gleason, Thomas G,

Harrison, J. Kevin,

Reardon, Michael J,

Popma, Jeffrey J,

Oh, Jae K,

Kleiman, Neal S,

Mumtaz, Mubashir,

Robinson, Newell,

Buchbinder, Maurice,

Heiser, John,

Adams, David H,

Tadros, Peter,

Merhi, William,

Yakubov, Steven J,

Deeb, G. Michael,

Chetcuti, Stan,

Hermiller, James,

Chenoweth, Sharla,

Maini, Brijeshwar

2014

Overview

Transcatheter aortic-valve replacement with a new self-expanding prosthesis was compared with surgical aortic-valve replacement in patients with aortic stenosis who were at high surgical risk. The rate of death from any cause at 1 year was lower in the TAVR group. Aortic stenosis is a debilitating disease in elderly persons that carries a dismal prognosis after symptom onset. 1 Although surgical aortic-valve replacement remains the standard treatment for aortic stenosis, 2 many patients are not suitable candidates for surgical replacement owing to an increased risk of death during surgery. 3 , 4 Transcatheter aortic-valve replacement (TAVR) with a balloon-expandable device improves survival, as compared with medical therapy, in patients with severe aortic stenosis who cannot undergo surgery. 5 Balloon-expandable TAVR and surgical aortic-valve replacement are associated with similar survival rates at 1 year among patients considered to be at high surgical risk, although the frequency of . . .

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Publisher

Massachusetts Medical Society

Subject

Aged

/ Aged, 80 and over

/ Aortic stenosis

/ Aortic Valve - surgery

/ Aortic Valve Stenosis - mortality

/ Aortic Valve Stenosis - surgery

/ Aortic Valve Stenosis - therapy