Asset Details
Do you wish to reserve the book?
Atopic Diseases, Allergic Sensitization, and Exposure to Traffic-related Air Pollution in Children
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Atopic Diseases, Allergic Sensitization, and Exposure to Traffic-related Air Pollution in Children
Do you wish to request the book?
Atopic Diseases, Allergic Sensitization, and Exposure to Traffic-related Air Pollution in Children
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Atopic Diseases, Allergic Sensitization, and Exposure to Traffic-related Air Pollution in Children
2008
Overview
In vitro studies, animal experiments, and human exposure studies have shown how ambient air pollution increases the risk of atopic diseases. However, results derived from observational studies are inconsistent.
To assess the relationship between individual-based exposure to traffic-related air pollutants and allergic disease outcomes in a prospective birth cohort study during the first 6 years of life.
We studied 2,860 children at the age of 4 years and 3,061 at the age of 6 years to investigate atopic diseases and allergic sensitization. Long-term exposure to particulate matter (PM(2.5)), PM(2.5) absorbance, and long-term exposure to nitrogen dioxide (NO(2)) was assessed at residential addresses using geographic information systems based regression models and air pollution measurements. The distance to the nearest main road was used as a surrogate for traffic-related air pollutants.
Strong positive associations were found between the distance to the nearest main road and asthmatic bronchitis, hay fever, eczema, and sensitization. A distance-dependent relationship could be identified, with the highest odds ratios (ORs) for children living less than 50 m from busy streets. For PM(2.5) absorbance, statistically significant effects were found for asthmatic bronchitis (OR, 1.56; 95% confidence interval [CI], 1.03-2.37), hay fever (OR, 1.59; 95% CI, 1.11-2.27), and allergic sensitization to pollen (OR, 1.40; 95% CI, 1.20-1.64). NO(2) exposure was associated with eczema, whereas no association was found for allergic sensitization.
This study provides strong evidence for increased risk of atopic diseases and allergic sensitization when children are exposed to ambient particulate matter.
Publisher
Am Thoracic Soc,American Thoracic Society
Subject
/ Air Pollution - adverse effects
/ Asthma
/ Bronchitis, Chronic - epidemiology
/ Bronchitis, Chronic - etiology
/ Child
/ Dermatitis, Atopic - epidemiology
/ Dermatitis, Atopic - etiology
/ Disease
/ Eczema
/ Environmental Exposure - adverse effects
/ Environmental Exposure - analysis
/ Female
/ Geographic information systems
/ Humans
/ Male
/ Particulate Matter - adverse effects
/ Particulate Matter - analysis
/ Respiratory Hypersensitivity - epidemiology
/ Respiratory Hypersensitivity - etiology
/ Rhinitis, Allergic, Seasonal - epidemiology
