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The Natural Course of Unruptured Cerebral Aneurysms in a Japanese Cohort
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Journal Article
The Natural Course of Unruptured Cerebral Aneurysms in a Japanese Cohort
2012
Overview
In this observational study involving 5720 Japanese adults who had saccular aneurysms that were 3 mm or larger, the annual risk of rupture was 0.95%. The risk of rupture varied according to the size, location, and shape of the aneurysm.
Although incidentally discovered cerebral aneurysms are common,
1
the management of these lesions has been controversial,
2
–
6
and the number of patients undergoing repair has been increasing.
7
Previous studies have shown that aneurysms smaller than 5 or 7 mm in the largest dimension rarely rupture and that aneurysms in the posterior circulation have a greater tendency to rupture than do those in the anterior circulation.
5
,
8
To determine the most appropriate treatment for individual patients, we need to have a better understanding of the risk of rupture of cerebral aneurysms.
We conducted a large, prospective cohort study of unruptured cerebral aneurysms . . .
Publisher
Massachusetts Medical Society
Subject
/ Aneurysm
/ Biological and medical sciences
/ Carotid Artery, Internal - pathology
/ Cerebral Arteries - pathology
/ Female
/ Humans
/ Intracranial Aneurysm - pathology
/ Male
/ Middle Cerebral Artery - pathology
/ Patients
/ Public health. Hygiene-occupational medicine
/ Rupture
/ Saccule
/ Vascular diseases and vascular malformations of the nervous system
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