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Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents
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Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents
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Journal Article
Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents
2018
Overview
In phase 2 and 3 randomized, controlled trials, baloxavir — an inhibitor of influenza cap-dependent endonuclease — showed evidence of clinical symptom relief and antiviral activity against influenza. However, influenza-resistant variants appeared to develop with treatment.
Publisher
Massachusetts Medical Society
Subject
/ Adult
/ Age
/ Antiviral Agents - administration & dosage
/ Antiviral Agents - adverse effects
/ Antiviral Agents - therapeutic use
/ Child
/ Endonucleases - antagonists & inhibitors
/ Female
/ Humans
/ Influenza, Human - drug therapy
/ Male
/ Oseltamivir - therapeutic use
/ Oxazines - administration & dosage
/ Patients
/ Proteins
/ Pyridines - administration & dosage
/ Thiepins - administration & dosage
/ Triazines - administration & dosage
/ Virus Replication - drug effects
/ Viruses
