Asset Details
Do you wish to reserve the book?
Biodegradation of bovine spongiform encephalopathy prions in compost
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Biodegradation of bovine spongiform encephalopathy prions in compost
Do you wish to request the book?
Biodegradation of bovine spongiform encephalopathy prions in compost
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Biodegradation of bovine spongiform encephalopathy prions in compost
2022
Overview
To reduce the transmission risk of bovine spongiform encephalopathy prions (PrP
BSE
), specified risk materials (SRM) that can harbour PrP
BSE
are prevented from entering the feed and food chains. As composting is one approach to disposing of SRM, we investigated the inactivation of PrP
BSE
in lab-scale composters over 28 days and in bin composters over 106–120 days. Lab-scale composting was conducted using 45 kg of feedlot manure with and without chicken feathers. Based on protein misfolding cyclic amplification (PMCA), after 28 days of composting, PrP
BSE
seeding activity was reduced by 3–4 log
10
with feathers and 3 log
10
without. Bin composters were constructed using ~ 2200 kg feedlot manure and repeated in 2017 and 2018. PMCA results showed that seeding activity of PrP
BSE
was reduced by 1–2 log
10
in the centre, but only by 1 log
10
in the bottom of bin composters. Subsequent assessment by transgenic (Tgbov XV) mouse bioassay confirmed a similar reduction in PrP
BSE
infectivity. Enrichment for proteolytic microorganisms through the addition of feathers to compost could enhance PrP
BSE
degradation. In addition to temperature, other factors including varying concentrations of PrP
BSE
and the nature of proteolytic microbial populations may be responsible for differential degradation of PrP
BSE
during composting.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
