Asset Details
Do you wish to reserve the book?
Stenotrophomonas tuberculopleuritidis sp. nov., a novel pathogenic Stenotrophomonas species isolated from tuberculous pleurisy patient
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Stenotrophomonas tuberculopleuritidis sp. nov., a novel pathogenic Stenotrophomonas species isolated from tuberculous pleurisy patient
Do you wish to request the book?
Stenotrophomonas tuberculopleuritidis sp. nov., a novel pathogenic Stenotrophomonas species isolated from tuberculous pleurisy patient
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Stenotrophomonas tuberculopleuritidis sp. nov., a novel pathogenic Stenotrophomonas species isolated from tuberculous pleurisy patient
2025
Overview
represents a group of bacteria that exhibit significant value in industrial and agricultural applications, while also posing pathogenic risks to humans. 704A1
was isolated from a patient with tuberculous pleurisy. Its 16S rRNA sequence showed the highest homology (99.72%) with a
strain without defined species classification. It is necessary to clarify the species 704A1
belonging to and its potential pathogenicity to humans.
Systematical evaluations including phenotypic and biochemical characteristics, antibiotic susceptibility, genomic sequencing were conducted. The pathogenicity and immunological characteristics were tested by intranasally inoculated C57BL/6J mice.
704A1
is Gram negative rod-shaped bacterium with flagella at single extreme. Showing highly similar with
, 704A1
also displayed distinct characteristic peaks in fatty acid profiling and MALDI-TOF analysis. 704A1
was resistance to 21 antibiotics, including four anti-tuberculosis drugs: rifampicin, streptomycin, rifabutin, and cycloserine. The average nucleotide identity (ANI) values of 704A1
compared to defined
species ranged from 80.03% to 89.6%, below than both the commonly accepted 95%-96% ANI threshold for prokaryote species and the 95% threshold suggested for
. Though no mortality was observed, 704A1
could cause severe consolidation in murine lung tissue and has the ability of hematogenous dissemination.
Results supported the classification of 704A1
(=GDMCC 1.4133
) as a novel species within the genus
, for which the name
sp. nov. is proposed. 704A1
is a multi-antibiotic resistance strain with potentially stronger pathogenicity than
and requires more clinical attention. The isolation of 704A1
underscored the importance of sustained surveillance and taxonomic clarity of
species emerging from clinical environments.
Publisher
Frontiers Media SA,Frontiers Media S.A
Subject
/ Anti-Bacterial Agents - pharmacology
/ Antitubercular Agents - pharmacology
/ Bacteria
/ Biofilms
/ Cellular and Infection Microbiology
/ Enzymes
/ Female
/ Flagella
/ Genes
/ Genomes
/ Gram-Negative Bacterial Infections - microbiology
/ Homology
/ Humans
/ Male
/ Mice
/ Multidrug resistant organisms
/ pathogen
/ patient
/ Patients
/ Pleurisy
/ Rifampin
/ RNA, Ribosomal, 16S - genetics
/ rRNA 16S
/ sputum
/ Stenotrophomonas - classification
/ Stenotrophomonas - drug effects
/ Stenotrophomonas - isolation & purification
/ Stenotrophomonas - pathogenicity
