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Rate of Intensive Care Unit admission and outcomes among patients with coronavirus: A systematic review and Meta-analysis
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Rate of Intensive Care Unit admission and outcomes among patients with coronavirus: A systematic review and Meta-analysis
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Journal Article
Rate of Intensive Care Unit admission and outcomes among patients with coronavirus: A systematic review and Meta-analysis
2020
Overview
The rate of ICU admission among patients with coronavirus varied from 3% to 100% and the mortality was as high as 86% of admitted patients. The objective of the systematic review was to investigate the rate of ICU admission, mortality, morbidity, and complications among patients with coronavirus.
A comprehensive strategy was conducted in PubMed/Medline; Science direct and LILACS from December 2002 to May 2020 without language restriction. The Heterogeneity among the included studies was checked with forest plot, χ2 test, I2 test, and the p-values. All observational studies reporting rate of ICU admission, the prevalence of mortality and its determinants among ICU admitted patients with coronavirus were included and the rest were excluded.
A total of 646 articles were identified from different databases and 50 articles were selected for evaluation. Thirty-seven Articles with 24983 participants were included. The rate of ICU admission was 32% (95% CI: 26 to 38, 37 studies and 32, 741 participants). The Meta-Analysis revealed that the pooled prevalence of mortality in patients with coronavirus disease in ICU was 39% (95% CI: 34 to 43, 37 studies and 24, 983 participants).
The Meta-Analysis revealed that approximately one-third of patients admitted to ICU with severe Coronavirus disease and more than thirty percent of patients admitted to ICU with a severe form of COVID-19 for better care died which warns the health care stakeholders to give attention to intensive care patients.
This Systematic review and Meta-Analysis was registered in Prospero international prospective register of systemic reviews (CRD42020177095) on April 9/2020.
Publisher
Public Library of Science,Public Library of Science (PLoS)
Subject
/ Betacoronavirus - physiology
/ Coronavirus Infections - epidemiology
/ Coronavirus Infections - mortality
/ Coronavirus Infections - pathology
/ Coronavirus Infections - physiopathology
/ COVID-19
/ Humans
/ Medicine
/ Medicine and Health Sciences
/ Middle East respiratory syndrome
/ Middle East Respiratory Syndrome Coronavirus - physiology
/ Patients
/ Research and Analysis Methods
/ Respiratory distress syndrome
/ Severe acute respiratory syndrome coronavirus 2
/ Severe acute respiratory syndrome-related coronavirus - physiology
