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Hemodynamic parameters impact the stability of distal stent graft-induced new entry
by
Xu, Xiao Yun
, Dong, Zhihui
, Ma, Tao
, Armour, Chlӧe H.
, Wang, Kaihong
in
639/166/985
/ 692/699/75/593/1301
/ Aorta
/ Cardiovascular system
/ Computed tomography
/ Computer applications
/ Dissection
/ Fluid dynamics
/ Hemodynamics
/ Humanities and Social Sciences
/ Hydrodynamics
/ Implants
/ multidisciplinary
/ Science
/ Science (multidisciplinary)
/ Shear stress
/ Thorax
/ Thromboembolism
/ Thrombosis
2023
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Hemodynamic parameters impact the stability of distal stent graft-induced new entry
by
Xu, Xiao Yun
, Dong, Zhihui
, Ma, Tao
, Armour, Chlӧe H.
, Wang, Kaihong
in
639/166/985
/ 692/699/75/593/1301
/ Aorta
/ Cardiovascular system
/ Computed tomography
/ Computer applications
/ Dissection
/ Fluid dynamics
/ Hemodynamics
/ Humanities and Social Sciences
/ Hydrodynamics
/ Implants
/ multidisciplinary
/ Science
/ Science (multidisciplinary)
/ Shear stress
/ Thorax
/ Thromboembolism
/ Thrombosis
2023
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While trying to remove the title from your shelf something went wrong :( Kindly try again later!
Do you wish to request the book?
Hemodynamic parameters impact the stability of distal stent graft-induced new entry
by
Xu, Xiao Yun
, Dong, Zhihui
, Ma, Tao
, Armour, Chlӧe H.
, Wang, Kaihong
in
639/166/985
/ 692/699/75/593/1301
/ Aorta
/ Cardiovascular system
/ Computed tomography
/ Computer applications
/ Dissection
/ Fluid dynamics
/ Hemodynamics
/ Humanities and Social Sciences
/ Hydrodynamics
/ Implants
/ multidisciplinary
/ Science
/ Science (multidisciplinary)
/ Shear stress
/ Thorax
/ Thromboembolism
/ Thrombosis
2023
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Hemodynamic parameters impact the stability of distal stent graft-induced new entry
Journal Article
Hemodynamic parameters impact the stability of distal stent graft-induced new entry
2023
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Overview
Stent graft-induced new entry tear (SINE) is a serious complication in aortic dissection patients caused by the stent-graft itself after thoracic endovascular aortic repair (TEVAR). The stability of SINE is a key indicator for the need and timing of reinterventions. This study aimed to understand the role of hemodynamics in SINE stability by means of computational fluid dynamics (CFD) analysis based on patient-specific anatomical information. Four patients treated with TEVAR who developed a distal SINE (dSINE) were included; two patients had a stable dSINE and two patients experienced expansion of the dSINE upon follow-up examinations. CFD simulations were performed on geometries reconstructed from computed tomography scans acquired upon early detection of dSINE in these patients. Computational results showed that stable dSINEs presented larger regions with low time-averaged wall shear stress (TAWSS) and high relative residence time (RRT), and partial thrombosis was observed at subsequent follow-ups. Furthermore, significant systolic antegrade flow was observed in the unstable dSINE which also had a larger retrograde flow fraction (RFF) on the SINE plane. In conclusion, this pilot study suggested that high RRT and low TAWSS may indicate stable dSINE by promoting thrombosis, whereas larger RFF and antegrade flows inside dSINE might be associated with its expansion.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
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