Journal Article

Comparison of Single-Session Dose Response Effects of Whole Body Vibration on Spasticity and Walking Speed in Persons with Spinal Cord Injury

Iddings, Jennifer A., Field-Fote, Edelle C., Estes, Stephen, Ray, Somu, Kirk-Sanchez, Neva J.

2018

Overview

Spasticity affects approximately 65% of persons with spinal cord injury (SCI) and negatively impacts function and quality of life. Whole body vibration (WBV) appears to reduce spasticity and improve walking function; however, the optimal dose (frequency/duration) is not known. We compared single-session effects of four different WBV frequency/duration dose conditions on spasticity and walking speed, in preparation for a planned multi-session study. Thirty-five participants with motor-incomplete SCI received four different doses of WBV: high frequency (50 Hz)/short duration (180 s), high frequency/long duration (360 s), low frequency (30 Hz)/short duration, and low frequency/long duration, plus a control intervention consisting of sham electrical stimulation. In all conditions, participants stood on the WBV platform for 45-s bouts with 1 min rest between bouts until the requisite duration was achieved. The frequency/duration dose order was randomized across participants; sessions were separated by at least 1 week. Quadriceps spasticity was measured using the pendulum test at four time points during each session: before, immediately after, 15 min after, and 45 min after WBV. Walking speed was quantified using the 10-m walk test at three time points during each session: baseline, immediately after, and 45 min after WBV. In the full group analysis, no frequency/duration combination was significantly different from the sham-control condition. In participants with more severe spasticity, a greater reduction in stretch reflex excitability was associated with the high frequency/long duration WBV condition. The sham-control condition was associated with effects, indicating that the activity of repeated sitting and standing may have a beneficial influence on spasticity. Trial registration: NCT02340910 (assigned 01/19/2015).

• Publisher: Elsevier Inc,Springer International Publishing,Springer Nature B.V
• Subject: Adolescent / Adult / Afferent input / Aged / Biomedical and Life Sciences / Biomedicine / Dose-response relationship / Electrical stimuli / Excitability / Female / Human Body / Humans / Hyperreflexia / Male / Middle Aged / Muscle Spasticity - therapy / Neurobiology / Neurology / Neurosciences / Neurosurgery / Oscillation / Pendulum test / Physical Therapy Modalities / Psychophysics - methods / Quadriceps muscle / Quality of life / Review / Severity of Illness Index / Spasticity / Spinal cord injuries / Spinal Cord Injuries - physiopathology / Spinal Cord Injuries - therapy / Stimulation / Stretch reflex / Time Factors / Vibration - therapeutic use / Walking / Walking Speed - physiology / Young Adult