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Zinc Phosphide Poisoning: From A to Z
by
Juárez-Martínez, Anabell
, Dorado-García, Ramsés
, Montes-Ventura, Daphne Marisol
, Rodríguez-Torres, Yessika Paola
, Madrigal-Anaya, Jesús del Carmen
, Jiménez-Ruiz, Ahgiel
in
Abnormalities
/ Acidosis
/ Antidotes
/ antioxidants
/ Care and treatment
/ Causes of
/ coconut oil
/ Cytochrome
/ Decontamination
/ Dosage and administration
/ Emergency medical care
/ Free radicals
/ Gases
/ Gastric lavage
/ Health aspects
/ Heart failure
/ Hemodynamics
/ Hydrochloric acid
/ Hypoxia
/ Ingestion
/ Lipids
/ magnesium sulphate
/ Metabolism
/ Patient outcomes
/ personal protective equipment
/ Pesticides
/ Phosphides
/ Phosphine
/ Phosphines
/ Physiological aspects
/ Poisoning
/ Poisons
/ Potassium
/ Review
/ Rodenticides
/ Toxicity
/ Toxicology
/ Urban agriculture
/ Zinc
/ Zinc phosphide
/ zinc phosphide poisoning
2023
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Zinc Phosphide Poisoning: From A to Z
by
Juárez-Martínez, Anabell
, Dorado-García, Ramsés
, Montes-Ventura, Daphne Marisol
, Rodríguez-Torres, Yessika Paola
, Madrigal-Anaya, Jesús del Carmen
, Jiménez-Ruiz, Ahgiel
in
Abnormalities
/ Acidosis
/ Antidotes
/ antioxidants
/ Care and treatment
/ Causes of
/ coconut oil
/ Cytochrome
/ Decontamination
/ Dosage and administration
/ Emergency medical care
/ Free radicals
/ Gases
/ Gastric lavage
/ Health aspects
/ Heart failure
/ Hemodynamics
/ Hydrochloric acid
/ Hypoxia
/ Ingestion
/ Lipids
/ magnesium sulphate
/ Metabolism
/ Patient outcomes
/ personal protective equipment
/ Pesticides
/ Phosphides
/ Phosphine
/ Phosphines
/ Physiological aspects
/ Poisoning
/ Poisons
/ Potassium
/ Review
/ Rodenticides
/ Toxicity
/ Toxicology
/ Urban agriculture
/ Zinc
/ Zinc phosphide
/ zinc phosphide poisoning
2023
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Zinc Phosphide Poisoning: From A to Z
by
Juárez-Martínez, Anabell
, Dorado-García, Ramsés
, Montes-Ventura, Daphne Marisol
, Rodríguez-Torres, Yessika Paola
, Madrigal-Anaya, Jesús del Carmen
, Jiménez-Ruiz, Ahgiel
in
Abnormalities
/ Acidosis
/ Antidotes
/ antioxidants
/ Care and treatment
/ Causes of
/ coconut oil
/ Cytochrome
/ Decontamination
/ Dosage and administration
/ Emergency medical care
/ Free radicals
/ Gases
/ Gastric lavage
/ Health aspects
/ Heart failure
/ Hemodynamics
/ Hydrochloric acid
/ Hypoxia
/ Ingestion
/ Lipids
/ magnesium sulphate
/ Metabolism
/ Patient outcomes
/ personal protective equipment
/ Pesticides
/ Phosphides
/ Phosphine
/ Phosphines
/ Physiological aspects
/ Poisoning
/ Poisons
/ Potassium
/ Review
/ Rodenticides
/ Toxicity
/ Toxicology
/ Urban agriculture
/ Zinc
/ Zinc phosphide
/ zinc phosphide poisoning
2023
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Journal Article
Zinc Phosphide Poisoning: From A to Z
2023
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Overview
Zinc phosphide is a rodenticide that is used in agricultural, urban and industrial environments in México. After ingestion, it reacts with hydrochloric acid, hydrolyzing into phosphine. It causes cellular hypoxia via mitochondrial toxicity, resulting in multiple organ dysfunction and death. There is no antidote or specific treatment for zinc phosphide toxicity. We present the case of a 45-year-old female who ingested zinc phosphide with suicidal intent. On arrival at the emergency department, she had multisystemic disorders. Supportive care, decontamination and antidotal therapy were initiated. Subsequently, she evolved to clinical improvement with a resolution of the biochemical abnormalities of tissue hypoperfusion. She was discharged on day 7 without complications. In this review, we provide updated therapeutic options and discuss their specific pathophysiological basis.
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