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Six Long-Standing Questions about Antibiotic Prophylaxis in Surgery

by De Simone, Belinda , Cui, Yunfeng , Gkiokas, George , Itani, Kamal M. F. , Rasa, Kemal , Shelat, Vishal G. , Isik, Arda , Cainzos, Miguel , Boermeester, Marja A. , Delibegovic, Samir , McNamara, Deborah A. , Pintar, Tadeja , Rickard, Jennifer , Demetrashvili, Zaza , Fry, Donald E. , Catena, Fausto , Sartelli, Massimo , de Jonge, Stijn W. , Barie, Philip S. , Labricciosa, Francesco Maria , Lohsiriwat, Varut , Coccolini, Federico , Marwah, Sanjay , Hardcastle, Timothy C. , Dellinger, E. Patchen

in Antibiotics / Antimicrobial agents / Bacteria / Clinical outcomes / Disease prevention / Drug dosages / Drug resistance / Health aspects / healthcare-associated infections / Infection / Infections / Patients / Pneumonia / Prevention / Prophylaxis / Questions / Review / Skin / Surgeons / Surgery / surgical antibiotic prophylaxis / Surgical site infections

2023

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2023

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2023

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Journal Article

Six Long-Standing Questions about Antibiotic Prophylaxis in Surgery

De Simone, Belinda,

Cui, Yunfeng,

Gkiokas, George,

Itani, Kamal M. F.,

Rasa, Kemal,

Shelat, Vishal G.,

Isik, Arda,

Cainzos, Miguel,

Boermeester, Marja A.,

Delibegovic, Samir,

McNamara, Deborah A.,

Pintar, Tadeja,

Rickard, Jennifer,

Demetrashvili, Zaza,

Fry, Donald E.,

Catena, Fausto,

Sartelli, Massimo,

de Jonge, Stijn W.,

Barie, Philip S.,

Labricciosa, Francesco Maria,

Lohsiriwat, Varut,

Coccolini, Federico,

Marwah, Sanjay,

Hardcastle, Timothy C.,

Dellinger, E. Patchen

2023

Overview

Surgical site infections (SSIs) are the most common adverse event occurring in surgical patients. Optimal prevention of SSIs requires the bundled integration of a variety of measures before, during, and after surgery. Surgical antibiotic prophylaxis (SAP) is an effective measure for preventing SSIs. It aims to counteract the inevitable introduction of bacteria that colonize skin or mucosa into the surgical site during the intervention. This document aims to guide surgeons in appropriate administration of SAP by addressing six key questions. The expert panel identifies a list of principles in response to these questions that every surgeon around the world should always respect in administering SAP.

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Publisher

MDPI AG,MDPI

Subject

Antibiotics

/ Antimicrobial agents