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The Combined Association of Skeletal Muscle Strength and Physical Activity on Mortality in Older Women: The HUNT2 Study
by
Wisløff, Ulrik
, Dalen, Håvard
, Karlsen, Trine
, Nauman, Javaid
, Langhammer, Arnulf
in
Aged
/ Aged women
/ Aged, 80 and over
/ Alcohol
/ Angina pectoris
/ Blood pressure
/ Body mass index
/ Cardiology
/ Cardiovascular disease
/ Cardiovascular diseases
/ Cardiovascular Diseases - mortality
/ Cause of Death
/ Cerebral infarction
/ Classification
/ Councils
/ Demographic aspects
/ Exercise
/ Family medical history
/ Female
/ Hand Strength
/ Health care
/ Health risk assessment
/ Heart attacks
/ Heart diseases
/ Hospitals
/ Humans
/ Internal Medicine
/ Ischemia
/ Leg - physiology
/ Medical imaging
/ Medicine
/ Mortality
/ Muscle Strength
/ Musculoskeletal system
/ Myocardial infarction
/ Norway - epidemiology
/ Older people
/ Physical activity
/ Physical fitness
/ Physiological aspects
/ Predictive Value of Tests
/ Prognosis
/ Proportional Hazards Models
/ Prospective Studies
/ Regression analysis
/ Science
/ Skeletal muscle
/ Sports medicine
/ Studies
/ United States
/ Womens health
2017
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The Combined Association of Skeletal Muscle Strength and Physical Activity on Mortality in Older Women: The HUNT2 Study
by
Wisløff, Ulrik
, Dalen, Håvard
, Karlsen, Trine
, Nauman, Javaid
, Langhammer, Arnulf
in
Aged
/ Aged women
/ Aged, 80 and over
/ Alcohol
/ Angina pectoris
/ Blood pressure
/ Body mass index
/ Cardiology
/ Cardiovascular disease
/ Cardiovascular diseases
/ Cardiovascular Diseases - mortality
/ Cause of Death
/ Cerebral infarction
/ Classification
/ Councils
/ Demographic aspects
/ Exercise
/ Family medical history
/ Female
/ Hand Strength
/ Health care
/ Health risk assessment
/ Heart attacks
/ Heart diseases
/ Hospitals
/ Humans
/ Internal Medicine
/ Ischemia
/ Leg - physiology
/ Medical imaging
/ Medicine
/ Mortality
/ Muscle Strength
/ Musculoskeletal system
/ Myocardial infarction
/ Norway - epidemiology
/ Older people
/ Physical activity
/ Physical fitness
/ Physiological aspects
/ Predictive Value of Tests
/ Prognosis
/ Proportional Hazards Models
/ Prospective Studies
/ Regression analysis
/ Science
/ Skeletal muscle
/ Sports medicine
/ Studies
/ United States
/ Womens health
2017
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The Combined Association of Skeletal Muscle Strength and Physical Activity on Mortality in Older Women: The HUNT2 Study
by
Wisløff, Ulrik
, Dalen, Håvard
, Karlsen, Trine
, Nauman, Javaid
, Langhammer, Arnulf
in
Aged
/ Aged women
/ Aged, 80 and over
/ Alcohol
/ Angina pectoris
/ Blood pressure
/ Body mass index
/ Cardiology
/ Cardiovascular disease
/ Cardiovascular diseases
/ Cardiovascular Diseases - mortality
/ Cause of Death
/ Cerebral infarction
/ Classification
/ Councils
/ Demographic aspects
/ Exercise
/ Family medical history
/ Female
/ Hand Strength
/ Health care
/ Health risk assessment
/ Heart attacks
/ Heart diseases
/ Hospitals
/ Humans
/ Internal Medicine
/ Ischemia
/ Leg - physiology
/ Medical imaging
/ Medicine
/ Mortality
/ Muscle Strength
/ Musculoskeletal system
/ Myocardial infarction
/ Norway - epidemiology
/ Older people
/ Physical activity
/ Physical fitness
/ Physiological aspects
/ Predictive Value of Tests
/ Prognosis
/ Proportional Hazards Models
/ Prospective Studies
/ Regression analysis
/ Science
/ Skeletal muscle
/ Sports medicine
/ Studies
/ United States
/ Womens health
2017
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The Combined Association of Skeletal Muscle Strength and Physical Activity on Mortality in Older Women: The HUNT2 Study
Journal Article
The Combined Association of Skeletal Muscle Strength and Physical Activity on Mortality in Older Women: The HUNT2 Study
2017
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Overview
To assess the isolated and combined associations of leg and arm strength with adherence to current physical activity guidelines with all-cause and cause-specific mortality in healthy elderly women.
This was a prospective cohort study of 2529 elderly women (72.6±4.8 years) from the Norwegian Healthy survey of Northern Trøndelag (second wave) (HUNT2) between August 15, 1995, and June 18, 1997, with a median of 15.6 years (interquartile range, 10.4-16.3 years) of follow-up. Chair-rise test and handgrip strength performances were assessed, and divided into tertiles. The hazard ratio (HR) of all-cause and cause-specific mortality by tertiles of handgrip strength and chair-rise test performance, and combined associations with physical activity were estimated by using Cox proportional hazard regression models.
We observed independent associations of physical activity and the chair-rise test performance with all-cause and cardiovascular mortality, and between handgrip strength and all-cause mortality. Despite following physical activity guidelines, women with low muscle strength had increased risk of all-cause mortality (HR chair test, 1.37; 95% CI, 1.07-1.76; HR handgrip strength, 1.39; 95% CI, 1.05-1.85) and cardiovascular disease mortality (HR chair test, 1.57; 95% CI, 1.01-2.42). Slow chair-test performance was associated with all-cause (HR, 1.32; 95% CI, 1.16-1.51) and cardiovascular disease (HR, 1.41; 95% CI, 1.14-1.76) mortality. The association between handgrip strength and all-cause mortality was dose dependent (P value for trend <.01).
Handgrip strength and chair-rise test performance predicted the risk of all-cause and CVD mortality independent of physical activity. Clinically feasible tests of skeletal muscle strength could increase the precision of prognosis, even in elderly women following current physical activity guidelines.
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