Asset Details
Do you wish to reserve the book?
Inhibitory effects of grape seed extract on lipases
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Inhibitory effects of grape seed extract on lipases
Do you wish to request the book?
Inhibitory effects of grape seed extract on lipases
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Inhibitory effects of grape seed extract on lipases
2003
Overview
The aim of the present study was to assess the effects of grape seed extract (GSE) on the fat-metabolizing enzymes pancreatic lipase, lipoprotein lipase, and hormone-sensitive lipase in vitro and evaluate its potential application as a treatment for obesity.
Crushed grape seeds were extracted in ethanol, and the extract was assayed for the measurement of inhibitory effects on pancreatic lipase and lipoprotein lipase activities and on lipolysis of 3T3-L1 adipocytes.
The GSE rich in bioactive phytochemicals showed inhibitory activity on the fat-metabolizing enzymes pancreatic lipase and lipoprotein lipase, thus suggesting that GSE might be useful as a treatment to limit dietary fat absorption and the accumulation of fat in adipose tissue. The observed reduction in intracellular lipolytic activity of cultured 3T3-L1 adipocytes may reduce the levels of circulating free fatty acids that have been linked to insulin resistance in obese patients.
The GSE rich in compounds that inhibit lipases may provide a safe, natural, and cost-effective weight control treatment.
Publisher
Elsevier Inc,Elsevier,Elsevier Limited
Subject
/ Adipose Tissue - drug effects
/ Animals
/ Biological and medical sciences
/ Diet
/ Enzyme Inhibitors - pharmacology
/ Enzymes
/ Ethanol
/ Intestinal Absorption - drug effects
/ Kinases
/ Lipase
/ Lipase - antagonists & inhibitors
/ Lipoprotein Lipase - antagonists & inhibitors
/ Lipoprotein Lipase - metabolism
/ Mice
/ Obesity
/ Obesity - prevention & control
/ Pancreas
/ Pharmacognosy. Homeopathy. Health food
/ Pharmacology. Drug treatments
/ Plant Extracts - pharmacology
/ Seeds
/ Vitis
