Asset Details
Do you wish to reserve the book?
The association between gestational diabetes and ASD and ADHD: a systematic review and meta-analysis
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
The association between gestational diabetes and ASD and ADHD: a systematic review and meta-analysis
Do you wish to request the book?
The association between gestational diabetes and ASD and ADHD: a systematic review and meta-analysis
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
The association between gestational diabetes and ASD and ADHD: a systematic review and meta-analysis
2021
Overview
There is growing evidence for a role of maternal diabetes in the pathogenesis of neurodevelopmental disorders. However, the specific association between gestational diabetes (GDM), as opposed to pre-gestational diabetes, has been poorly isolated. Thus the aim was to systematically review and meta-analyse literature pertaining to prevalence and risk for two neurodevelopmental disorders: autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD), when exposed to GDM. PubMed, Cochrane Library, EMBASE, PsycINFO and CINAHL were systematically searched for eligible literature, with forward and backward citation tracking. Screening for eligibility, risk of bias assessment and data extraction were performed by two independent reviewers. 18 studies measuring ASD and 15 measuring ADHD met inclusion criteria. On meta-analysis there was an increased risk of ASD (OR 1.42; 95% CI 1.22, 1.65) but not ADHD (OR 1.01; 95% CI 0.79, 1.28). We discuss potential mechanisms for these differing risks. Greater understanding of risk factors, including GDM, for these neurodevelopmental disorders and potential mechanisms may help inform strategies aimed at prevention of exposure to these adversities during pregnancy.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
/ 692/499
/ Adult
/ Attention Deficit Disorder with Hyperactivity - epidemiology
/ Attention Deficit Disorder with Hyperactivity - etiology
/ Attention Deficit Disorder with Hyperactivity - pathology
/ Attention deficit hyperactivity disorder
/ Autism
/ Autism Spectrum Disorder - epidemiology
/ Autism Spectrum Disorder - etiology
/ Autism Spectrum Disorder - pathology
/ Child
/ Diabetes Complications - complications
/ Diabetes Complications - epidemiology
/ Diabetes Complications - pathology
/ Diabetes, Gestational - epidemiology
/ Diabetes, Gestational - pathology
/ Female
/ Humanities and Social Sciences
/ Humans
/ Male
/ Neurodevelopmental disorders
/ Science
