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Pediatric Systemic Lupus Erythematous in COVID-19 Era

by Lupu, Ancuta , Dragan, Felicia , Ioniuc, Ileana , Butnariu, Lacramioara Ionela , Lupu, Vasile Valeriu , Miron, Ingrith Crenguta , Mocanu, Adriana , Gavrilovici, Cristina , Raileanu, Anca Adam , Azoicai, Alice , Starcea, Iuliana Magdalena

in Adults / Antibodies / Asymptomatic / Autoimmune Diseases / Child / Children / Comorbidity / Coronaviruses / COVID-19 / COVID-19 infection / Demographic aspects / Development and progression / Diagnosis / Disease control / Diseases / Drugs / Epidemiology / Health aspects / Hospitalization / Humans / Immune system / immunosuppression / Immunosuppression Therapy / Immunosuppressive agents / Infections / Lupus / lupus erythematosus / Lupus Erythematosus, Systemic - complications / Medical research / Mortality / Pandemics / Pediatrics / prognosis / Remission (Medicine) / Review / Rheumatic diseases / risk / Severe acute respiratory syndrome coronavirus 2 / Systemic lupus erythematosus / vaccine / Viral infections

2023

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Pediatric Systemic Lupus Erythematous in COVID-19 Era

2023

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Pediatric Systemic Lupus Erythematous in COVID-19 Era

2023

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Journal Article

Pediatric Systemic Lupus Erythematous in COVID-19 Era

Lupu, Ancuta,

Dragan, Felicia,

Ioniuc, Ileana,

Butnariu, Lacramioara Ionela,

Lupu, Vasile Valeriu,

Miron, Ingrith Crenguta,

Mocanu, Adriana,

Gavrilovici, Cristina,

Raileanu, Anca Adam,

Azoicai, Alice,

Starcea, Iuliana Magdalena

2023

Overview

Pediatric systemic lupus erythematosus is a chronic autoimmune disorder with a highly variable course and prognosis. It results in functional abnormalities in the immune system due to intrinsic factors and the use of immunosuppressive therapies associated with underlying comorbidities seem to increase the risk of severe COVID-19 and poor outcomes of the disease in pediatric systemic lupus erythematosus (SLE) patients. The aim of this review is to obtain a better understanding of the existing link between this new viral infection and pediatric lupus. We have analyzed the characteristics of newly diagnosed cases of pediatric SLE following COVID-19 which have been reported in the literature and which describe the impact that COVID-19 has on patients already suffering with pediatric SLE.

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Publisher

MDPI AG,MDPI

Subject

Adults

/ Antibodies

/ Asymptomatic

/ Autoimmune Diseases

/ Child

/ Children

/ Comorbidity