Journal Article

Nano-drug delivery systems in wound treatment and skin regeneration

Du, Yong-Zhong, Lu, Kong-jun, Wang, Wei, Huang, Qiao-ling, Yu, Chao-heng

2019

Overview

Skin damages are defined as one of most common lesions people suffer from, some of wounds are notoriously difficult to eradicate such as chronic wounds and deep burns. Existing wound therapies have been proved to be inadequate and far from satisfactory. The cutting-edge nanotechnology offers an unprecedented opportunity to revolutionize and invent new therapies or boost the effectiveness of current medical treatments. In particular, the nano-drug delivery systems anchor bioactive molecules to applied area, sustain the drug release and explicitly enhance the therapeutic efficacies of drugs, thus making a fine figure in field relevant to skin regeneration. This review summarized and discussed the current nano-drug delivery systems holding pivotal potential for wound healing and skin regeneration, with a special emphasis on liposomes, polymeric nanoparticles, inorganic nanoparticles, lipid nanoparticles, nanofibrous structures and nanohydrogel.

• Publisher: BioMed Central,BioMed Central Ltd,BMC
• Subject: Animals / Biocompatible Materials - chemistry / Biotechnology / Care and treatment / Chemistry / Chemistry and Materials Science / Drug delivery systems / Drug Delivery Systems - methods / Drug Liberation / Drugs / Humans / Hydrogels - chemistry / Lipids - chemistry / Liposomes - chemistry / Molecular Medicine / Nano-drug delivery system / Nanoparticles - chemistry / Nanotechnology / Polymers - chemistry / Regeneration / Regenerative medicine / Review / Skin Physiological Phenomena / Skin regeneration / Technology application / Vehicles / Wound Healing - drug effects / Wound treatment / Wounds and injuries