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Study of Steroid Effects on Graft and Inner ear Outcomes in Tympanoplasty: Randomized Controlled Trial
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Study of Steroid Effects on Graft and Inner ear Outcomes in Tympanoplasty: Randomized Controlled Trial
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Journal Article
Study of Steroid Effects on Graft and Inner ear Outcomes in Tympanoplasty: Randomized Controlled Trial
2018
Overview
More studies are needed to investigate the side effects of steroids in tympanoplasty, owing to the paucity of such studies in the literature. This randomized, controlled clinical trial included 59 patients with chronic otitis media who underwent tympanoplasty and were randomized after surgery to a systemic steroid or no steroid treatment. Patients were randomized into two groups. Perforation size, graft outcome, and complications such as tinnitus and hearing loss were compared between the two groups. Postsurgical steroid injection had no effect on graft outcome ( p = 0.927) or tinnitus ( p = 0.478). Tympanic membrane perforation ( p = 0.92), plaque size ( p = 0.94), bleeding amount ( p = 0.38), and mucosal status ( p = 0.96) during surgery had no effect on graft outcome after the tympanoplasty. In conclusion, administration of steroids after tympanoplasty failed to improve outcome and may put the patient at risk of side effects.
Publisher
SAGE Publications,Sage Publications, Inc,SAGE PUBLICATIONS, INC
Subject
/ Analysis
/ Ear
/ Female
/ Graft Survival - drug effects
/ Humans
/ Male
/ Otitis Media - complications
/ Steroids
/ Steroids - administration & dosage
/ Surgeons
/ Surgery
/ Tinnitus
/ Tympanic Membrane - transplantation
/ Tympanic Membrane Perforation - etiology
/ Tympanic Membrane Perforation - surgery
/ Vertigo
