Journal Article

Congenital aniridia with cataract: case series

Zhang, Jing Shang, Vishal, Jhanji, You, Qi Sheng, Liu, Xue, Zhao, Jing, Xiong, Ying, Li, Jing, Tsai, Frank F., Huang, Yao, Wang, Jin Da, Li, Xiao Xia, Wan, Xiu Hua

2017

Overview

Background This study evaluates patients with congenital aniridia and cataract who underwent phacoemulsification, capsular tension ring placement, and foldable intraocular lens implantation. Methods In this prospective case series, 10 patients (17 eyes) underwent cataract surgery via a 3.2 mm clear corneal incision. A continuous circular capsulorhexis with <6 mm diameter was employed. A capsular tension ring and HOYA yellow foldable posterior chamber intraocular lens was implanted. All patients wore color contact lenses postoperatively. Paired t test was used to compare visual acuity, intraocular pressure, and corneal endothelial changes before and after surgery. Results A single surgeon performed all surgeries. The best-corrected visual acuity improved from value 1.03 ± 0.27LogMAR preoperatively to value 0.78 ± 0.26LogMAR postoperatively ( p  = 0.000). The photophobic symptoms improved significantly after surgery. The mean corneal endothelial cell density before and after surgery was 3280 ± 473 cells/mm2 and 2669 ± 850 cells/mm2, respectively ( p  = 0.006). None of the patients developed corneal endothelial decompensation or secondary glaucoma after surgery. Conclusions Treatment of congenital aniridia and coexistent cataract by phacoemulsification, posterior chamber foldable lens implantation, capsular tension ring placement was safe and effective. Use of colored contact lenses in the postoperative period can reduce photophobic symptoms in this group of patients. Trial registration ChiCTR-OOC-17011638 (retrospectively registered at 12,June,2017)

• Publisher: BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
• Subject: Acuity / Adolescent / Adult / Aniridia / Aniridia - complications / Aniridia - diagnosis / Aniridia - surgery / Capsular tension ring / Care and treatment / Cataract / Cataract - complications / Cataract - diagnosis / Cataract - physiopathology / Cataract and refractive surgery / Cataract removal surgery / Cataracts / Cell density / Child / Child, Preschool / Color / Color artificial lens / Comparative analysis / Congenital aniridia / Contact lenses / Cornea / Eye lens / Eye surgery / Female / Glaucoma / Health aspects / Humans / Lenses, Intraocular / Male / Medical prognosis / Medicine / Medicine & Public Health / Middle Aged / Ophthalmology / Patient outcomes / Patients / Phacoemulsification / Phacoemulsification - methods / Prospective Studies / Research Article / Surgery / Tomography, Optical Coherence / Visual Acuity / Young Adult