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The properties of TREM1 and its emerging role in pain-related diseases
by
Ge, Zhaoming
, Sun, Songtang
, Fan, Zhenzhen
, Wang, Longde
in
Amino acids
/ Analysis
/ Animals
/ Biomedical and Life Sciences
/ Biomedicine
/ Chronic pain
/ Humans
/ Hyperalgesia
/ Immune response
/ Immunity (Disease)
/ Inflammation
/ Inflammation - pathology
/ Inflammatory diseases
/ Ligands
/ Microglia
/ Migraine
/ Myeloid cells
/ Nervous system
/ Neurology
/ Neuroplasticity
/ Neurosciences
/ Neutrophils
/ Pain
/ Pain - metabolism
/ Pain - pathology
/ Pain management
/ Pathogenesis
/ Proteins
/ Psychopharmacology
/ Review
/ Sepsis
/ Signal Transduction
/ Spinal cord
/ TREM1
/ Triggering Receptor Expressed on Myeloid Cells-1 - chemistry
/ Triggering Receptor Expressed on Myeloid Cells-1 - metabolism
2025
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The properties of TREM1 and its emerging role in pain-related diseases
by
Ge, Zhaoming
, Sun, Songtang
, Fan, Zhenzhen
, Wang, Longde
in
Amino acids
/ Analysis
/ Animals
/ Biomedical and Life Sciences
/ Biomedicine
/ Chronic pain
/ Humans
/ Hyperalgesia
/ Immune response
/ Immunity (Disease)
/ Inflammation
/ Inflammation - pathology
/ Inflammatory diseases
/ Ligands
/ Microglia
/ Migraine
/ Myeloid cells
/ Nervous system
/ Neurology
/ Neuroplasticity
/ Neurosciences
/ Neutrophils
/ Pain
/ Pain - metabolism
/ Pain - pathology
/ Pain management
/ Pathogenesis
/ Proteins
/ Psychopharmacology
/ Review
/ Sepsis
/ Signal Transduction
/ Spinal cord
/ TREM1
/ Triggering Receptor Expressed on Myeloid Cells-1 - chemistry
/ Triggering Receptor Expressed on Myeloid Cells-1 - metabolism
2025
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Do you wish to request the book?
The properties of TREM1 and its emerging role in pain-related diseases
by
Ge, Zhaoming
, Sun, Songtang
, Fan, Zhenzhen
, Wang, Longde
in
Amino acids
/ Analysis
/ Animals
/ Biomedical and Life Sciences
/ Biomedicine
/ Chronic pain
/ Humans
/ Hyperalgesia
/ Immune response
/ Immunity (Disease)
/ Inflammation
/ Inflammation - pathology
/ Inflammatory diseases
/ Ligands
/ Microglia
/ Migraine
/ Myeloid cells
/ Nervous system
/ Neurology
/ Neuroplasticity
/ Neurosciences
/ Neutrophils
/ Pain
/ Pain - metabolism
/ Pain - pathology
/ Pain management
/ Pathogenesis
/ Proteins
/ Psychopharmacology
/ Review
/ Sepsis
/ Signal Transduction
/ Spinal cord
/ TREM1
/ Triggering Receptor Expressed on Myeloid Cells-1 - chemistry
/ Triggering Receptor Expressed on Myeloid Cells-1 - metabolism
2025
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The properties of TREM1 and its emerging role in pain-related diseases
Journal Article
The properties of TREM1 and its emerging role in pain-related diseases
2025
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Overview
The TREM1 receptor, a member of the TREMs family, is expressed by myeloid cells and functions as an initiator or enhancer of the inflammatory response, playing a pivotal role in the regulation of inflammation. In recent years, it has been found that TREM1-mediated inflammatory response is involved in the regulation of pain-related diseases. This article provides an extensive review on the structural characteristics and distribution patterns, ligand, signaling pathways, inhibitors, and pathophysiological roles of TREM1 in pain disorders aiming to further elucidate its biological function and offer novel insights for clinical interventions targeting pain-related diseases.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
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