Journal Article

Analysis of public perceptions on the use of artificial intelligence in genomic medicine

Harrison, Jack E., Lynch, Fiona, Stark, Zornitza, Vears, Danya F.

2024

Overview

Purpose Next generation sequencing has led to the creation of large pools of genomic data with analysis rather than data generation now the limiting factor. Artificial intelligence (AI) may be required to optimize the benefits of these data, but little is known about how the public feels about the use of AI in genomics. Methods We conducted focus groups with members of the Australian public. Participants were recruited via social media advertisements. We explored potential uses of AI in genomic medicine, the benefits, risks, and the possible social implications of its use. Results Participants ( n  = 34) largely felt comfortable with AI analysing their own genomic data and generally agreed about its benefits. Concerns were raised over data security, the potential for misdiagnosis, and bias AI may perpetuate. Many participants wanted checking mechanisms for when results were generated using AI. Conclusions The insights gained from these discussions help to understand public concerns around the use of AI in genomic medicine. Our findings can help to inform both policies around genomic AI and how to educate the public on its use. Graphical abstract

• Publisher: BioMed Central,Springer Nature B.V,BMC
• Subject: Adult / Aged / Algorithms / Artificial Intelligence / Australia / Bioethics / Bioinformatics / Biomedical and Life Sciences / Biomedicine / Brain research / Data integrity / Female / Focus Groups / Genomic analysis / Genomics / High-Throughput Nucleotide Sequencing / Human error / Human Genetics / Humans / Machine learning / Male / Medicine / Middle Aged / Next-generation sequencing / Perceptions / Professional ethics / Professionals / Proteomics / Public Opinion / Qualitative / Trust